FB2025_01 , released February 20, 2025
Allele: Dmel\elg13R7
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General Information
Symbol
Dmel\elg13R7
Species
D. melanogaster
Name
FlyBase ID
FBal0296220
Feature type
allele
Associated gene
Dmel\elg1
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Hayashi et al., 2014)
Progenitor genotype
Cytology
Description

Nucleotide substitution: G?A.

(Hayashi et al., 2014)

Amino acid replacement: W212term.

(Hayashi et al., 2014)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:16,133,149..16,133,149 [+]
Nucleotide change:

G16133149A

Reported nucleotide change:

G?A

Amino acid change:

W212term | elg1-PC; W156term | elg1-PD; W156term | elg1-PE

Reported amino acid change:

W212term

Comment:

TGG to TGA nonsense mutation.

(Hayashi et al., 2014)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Nurse cell nuclei derived from homozygous germline clones are smaller than normal and apparently underreplicated.

      elg13R7/elg1e01159 adults show no significant difference in body size compared to controls. The macrochaetae on the notum are shorter than normal and females are sterile.

      (Hayashi et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      elg1e01159

      (Hayashi et al., 2014)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      elg13R7
      (Hayashi et al., 2014)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)