FlyBase Allele Report: Dmel\stg[UAS.Tag:HA]

General Information

Symbol

Dmel\stg^UAS.Tag:HA

Species

D. melanogaster

Name

FlyBase ID

FBal0296614

Feature type

allele

Associated gene

Dmel\stg

Associated Insertion(s)

Carried in Construct

P{UAS-stg.HA}

Also Known As

UAS-stg, UAS-StgHA

Key Links

Transgenic product class

wild_type

(Matakatsu, 2014.6.24)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Matakatsu, 2014.6.24)

Mutagen

in vitro construct

(Matakatsu, 2014.6.24)

Progenitor genotype

Carried in construct

P{UAS-stg.HA}

Cytology

Description

Expresses stg tagged with Tag:HA under the control of UAS.

(Matakatsu, 2014.6.24)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

stg

Tagged with

Tag:HA

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

exacerbates cancer

modeled by N^ICN.UAS

(Wang et al., 2021)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal mitotic cell cycle | third instar larval stage, with Scer\GAL4^ap-md544

(Gerlach et al., 2018)

abnormal wound healing | larval stage, with Scer\GAL4^repo

(Li et al., 2020)

increased occurrence of cell division | third instar larval stage, with Scer\GAL4^ap-md544

(Gerlach et al., 2018)

Phenotype Manifest In

larval multidendritic class IV neuron, with Scer\GAL4^repo

(Li et al., 2020)

wing disc dorsal compartment | third instar larval stage, with Scer\GAL4^ap-md544

(Gerlach et al., 2018)

Detailed Description

Statement

Reference

The expression of stg^UAS.Tag:HA from the second instar larval stage under the combined control of Scer\GAL4^ap-md544 and Gal80[ts] leads to an accelerated G2/M progression and to a moderate polyploidy/aneuploidy in the third instar larval wing disc dorsal compartment, but does not affect the growth of the wing disc, as compared to controls.

(Gerlach et al., 2018)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Diap1^UAS.cUa, Scer\GAL4^ap-md544, pnut^GD1512, stg^UAS.Tag:HA has abnormal size | third instar larval stage phenotype

(Gerlach et al., 2018)

Phenotype Manifest In

Other

Statement

Reference

Diap1^UAS.cUa, Scer\GAL4^ap-md544, pnut^GD1512, stg^UAS.Tag:HA has wing disc dorsal compartment | third instar larval stage phenotype

(Gerlach et al., 2018)

Additional Comments

Genetic Interactions

Statement

Reference

The triple co-expression of pnut^GD1512, Diap1^UAS.cUa and stg^UAS.Tag:HA from the second instar larval stage under the combined control of Scer\GAL4^ap-md544 and Gal80[ts] leads to the significant enlargement of the third instar larval wing disc dorsal compartment, as compared to the pnut^GD1512, Diap1^UAS.cUa double expression condition.

(Gerlach et al., 2018)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

56562

w^*; P{UAS-stg.HA}2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

stg^{Scer\UAS.T:Ivir\HA1}

stg^UAS.Tag:HA

Name Synonyms

Secondary FlyBase IDs

References (9)

Report Sections

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