FB2018_06, released Dec 21, 2018
All FlyBase archives from FB2014_04 until FB2018_05 are temporarily unavailable.
Allele: Dmel\jet
set
FB2018_06, released Dec 21, 2018
All FlyBase archives from FB2014_04 until FB2018_05 are temporarily unavailable.
Allele: Dmel\jet
set
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General Information
Symbol
Dmel\
jet
set
Species
D. melanogaster
Name
FlyBase ID
FBal0296640
Feature type
allele
Associated gene
Dmel\jet
Associated Insertion(s)
Carried in Construct
Genomic Maps
GBrowse
JBrowse
Help me choose
Allele class
loss of function allele
Mutagen
ethyl methanesulfonate
Nature of the Allele
Allele class
loss of function allele
(
Lamba et al., 2014
)
Mutagen
ethyl methanesulfonate
(
Lamba et al., 2014
)
Mutations Mapped to the Genome
Type
Location
Additional Notes
References
point mutation
2L:4,948,991..4,948,991 [-]
Nucleotide change:
C4948991T
Amino acid change:
T228I | jet-PA; T228I | jet-PB
Reported amino acid change:
T228I
Comment:
Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.
(
Lamba et al., 2014
)
Associated Sequence Data
DDBJ
/
EMBL
/
GenBank
DNA sequence
Protein sequence
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference
Amino acid replacement: T228I.
(
Lamba et al., 2014
)
Expression Data
Reporter Expression
Additional Information
Statement
Reference
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Model Data
Disease Ontology
Models ( 0 )
Disease
Evidence
References
Interactions ( 0 )
Disease
Interaction
References
Comments ( 0 )
Phenotypic Data
Phenotypic Class
locomotor rhythm defective
|
adult stage
(
Lamba et al., 2014
)
Phenotype Manifest In
Detailed Description
Statement
Reference
Mutant flies remain robustly rhythmic under constant light conditions, in construct to wild-type controls. Behavioral phase shifts after short light pulses applied early (ZT15) or late (ZT21) at night are almost completely abolished in mutant flies.
(
Lamba et al., 2014
)
External Data
Linkouts
Interactions
Show genetic interaction network for
Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to complement
jet
c
(
Lamba et al., 2014
)
jet
r
(
Lamba et al., 2014
)
Rescued by
jet
set
is rescued by
Scer\GAL4
tim.PE
/
jet
UAS.cKa
(
Lamba et al., 2014
)
jet
set
is rescued by
jet
UAS.cKa
/
Scer\GAL4
Mai179
(
Lamba et al., 2014
)
jet
set
is rescued by
Scer\GAL4
Dvir\Pdf.1.9
/
jet
UAS.cKa
(
Lamba et al., 2014
)
Partially rescued by
jet
set
is partially rescued by
jet
UAS.cKa
/
Scer\GAL4
P2.4.Pdf
(
Lamba et al., 2014
)
Not rescued by
jet
set
is not rescued by
jet
UAS.cKa
/
Scer\GAL4
Clk.4.1M
(
Lamba et al., 2014
)
jet
set
is not rescued by
Scer\GAL4
dimm-929
/
jet
UAS.cKa
(
Lamba et al., 2014
)
jet
set
is not rescued by
jet
UAS.cKa
/
Scer\GAL4
Mai179
/
Scer\GAL80
Pdf.PS
(
Lamba et al., 2014
)
Comments
Expression of
jet
Scer\UAS.cKa
under the control of either
Scer\GAL4
tim.PE
,
Scer\GAL4
Dvir\Pdf.1.9
or
Scer\GAL4
Mai179
in
jet
set
flies rescues the reduction in phase shifts in response to short light pulses applied early (ZT15) or late (ZT21) at night. Expression under the control of either
Scer\GAL4
Clk.4.1M
or
Scer\GAL4
dimm-929
fails to rescue this defect, while expression under the control of
Scer\GAL4
P2.4.Pdf
results in slight rescue at ZT15, but not at ZT21. Expression of
jet
Scer\UAS.cKa
under the control of
Scer\GAL4
Mai179
in the presence of
Scer\GAL80
Pdf.PS
fails to rescue the reduction in phase shifts in response to short light pulses at ZT15 or ZT21.
(
Lamba et al., 2014
)
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
jet
set
(
Lamba et al., 2014
)
Name Synonyms
Secondary FlyBase IDs
References (1)
Report Sections
General Information
Nature of the Allele
Expression Data
Human Disease Model Data
Phenotypic Data
Interactions
Complementation and Rescue Data
Images
Stocks
Notes On Origin
Crossreferences
Synonyms and Secondary IDs
References