FB2021_01, released Feb 18, 2021

Allele: Dmel\ermzf1.2A.UAS

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General Information
Symbol
Dmel\ermzf1.2A.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0297355
Feature type
allele
Associated gene
Dmel\erm
Associated Insertion(s)
Carried in Construct
P{UAS-erm.zf1.2A}
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - regulatory fusion
(Janssens et al., 2014)
in vitro construct - deletion
(Janssens et al., 2014)
in vitro construct - site directed mutagenesis
(Janssens et al., 2014)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Carried in construct
      P{UAS-erm.zf1.2A}
      Cytology
      Nature of the lesion
      Statement
      Reference

      UAS regulatory sequences drive expression of a mutant form of erm containing only the zinc finger domains, and in which the first zinc finger contains an alanine to cysteine substitution.

      (Janssens et al., 2014)
      Allele components
      Product class / Tool use(s)
      Regulatory region(s)
      UAS
      Encoded product / tool
      erm
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of ermzf1.2A.Scer\UAS under the control of Scer\GAL4wor.PA induces premature differentiation of all eight type II neuroblasts in a larval brain lobe.

      (Janssens et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4GMR9D11/ermzf1.2A.UAS rescues Df(2L)erm2/erm1

      (Janssens et al., 2014)
      Comments

      Expression of ermzf1.2A.Scer\UAS under the control of an insertion of Scer\GAL4GMR9D11 that expresses in ase[+] immature Intermediate Neural Progenitors (INPs) (P{GMR9D11-GAL4}attP2) rescues the supernumerary neuroblast phenotype seen in erm1/Df(2L)erm2 mutant larval brains.

      (Janssens et al., 2014)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ermzf1.2A.Scer\UAS
      ermzf1.2A.UAS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)