FlyBase Allele Report: Scer\GAL4[tim.PU]

General Information

Symbol

Scer\GAL4^tim.PU

Species

S. cerevisiae

Name

Saccharomyces cerevisiae UAS construct a of Unknown

FlyBase ID

FBal0298050

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{tim-GAL4.U}

Also Known As

tim-Gal4, TimGal4, TG4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Beuchle et al., 2012)

Progenitor genotype

Carried in construct

P{tim-GAL4.U}

Cytology

Description

GAL4 expression is driven by tim regulatory sequences.

(Beuchle et al., 2012)

Allele components

Component

Use(s)

Regulatory region(s)

tim

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

l-LNv neuron

(Kucherenko et al., 2016)

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal circadian behavior | adult stage, with Dh44-R1^KK108591

(King et al., 2017)

abnormal circadian rhythm, with Rnb^GD12299

(Kozlov et al., 2017)

abnormal circadian rhythm | adult stage, with CoRest^GD10500

(Lv et al., 2024)

abnormal circadian rhythm | adult stage, with HDAC1^GD4513

(Lv et al., 2024)

abnormal circadian rhythm | adult stage, with Kdm2^UAS.EGFP

(Zheng et al., 2018)

abnormal circadian rhythm | adult stage, with Kdm2^UAS.EGFP, Scer\GAL80^Pdf.PS

(Zheng et al., 2018)

abnormal circadian rhythm | adult stage, with Kdm4A^GD9133

(Lv et al., 2024)

abnormal circadian rhythm | adult stage, with Mmus\Nos2^Mac.UAS

(Kozlov et al., 2020)

abnormal circadian rhythm | adult stage, with nmo^KK107867

(Yu et al., 2011)

abnormal circadian rhythm | adult stage, with nmo^KK109009

(Yu et al., 2011)

abnormal circadian rhythm | adult stage, with nmo^UAS.cUa.GFP

(Yu et al., 2011)

abnormal circadian rhythm | adult stage, with Nos^GD12013

(Kozlov et al., 2020)

abnormal circadian rhythm | adult stage, with per^UAS.cYa

(Xue et al., 2019)

abnormal circadian rhythm | adult stage, with Pp1-87B^GD11720

(Xue et al., 2019)

abnormal circadian rhythm | adult stage, with Pp1-87B^HMS00409

(Xue et al., 2019)

abnormal circadian rhythm | adult stage, with Su(var)3-3^GD9296

(Lv et al., 2024)

abnormal circadian rhythm | adult stage, with Sur-8^HMJ22782

(Xue et al., 2019)

abnormal circadian rhythm | adult stage, with Sur-8^HMJ22782, Sur-8^JF03236

(Xue et al., 2019)

abnormal circadian rhythm | adult stage, with Sur-8^JF03236

(Xue et al., 2019)

abnormal circadian rhythm | adult stage, with Sur-8^UAS.Tag:FLAG

(Xue et al., 2019)

abnormal circadian rhythm | adult stage | progressive, with LKRSDH^HMC03424

(Lv et al., 2024)

abnormal locomotor rhythm, with Hr51^RNAi.UAS.a

(Beuchle et al., 2012)

abnormal locomotor rhythm | adult stage, with mir-279^UAS.pLUC

(Sun et al., 2015)

abnormal locomotor rhythm | adult stage, with mir-996^{UAS.DsRed(Unk)}

(Sun et al., 2015)

abnormal locomotor rhythm | adult stage, with tim^{UAS.cold.Tag:FLAG}

(Martin Anduaga et al., 2019)

abnormal locomotor rhythm | adult stage, with tim^{UAS.L.Tag:FLAG}

(Martin Anduaga et al., 2019)

abnormal locomotor rhythm | adult stage, with tim^{UAS.sc.Tag:FLAG}

(Martin Anduaga et al., 2019)

abnormal sleep, with tim^RNAi.UAS.cTa

(Liu and Zhao, 2014)

lethal, with NiPp1^UAS.EGFP

(Xue et al., 2019)

lethal, with NiPp1^UAS.Tag:HA

(Xue et al., 2019)

lethal, with Pp1-87B^HMS00409

(Xue et al., 2019)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^tim.PU, Sur-8^JF03236 has abnormal circadian rhythm | adult stage phenotype, enhanceable by Scer\GAL4^tim.PU/per^UAS.cYa

(Xue et al., 2019)

Suppressed by

Statement

Reference

Scer\GAL4^tim.PU, Sur-8^JF03236 has abnormal circadian rhythm | adult stage phenotype, suppressible | partially by Scer\GAL4^tim.PU/per^UAS.cYa

(Xue et al., 2019)

Enhancer of

Statement

Reference

Scer\GAL4^tim.PU/Su(var)3-3^GD9296 is an enhancer of abnormal circadian rhythm | adult stage | dominant phenotype of CoRest^MI08173

(Lv et al., 2024)

Scer\GAL4^tim.PU/per^UAS.cYa is an enhancer of abnormal circadian rhythm | adult stage phenotype of Scer\GAL4^tim.PU, Sur-8^JF03236

(Xue et al., 2019)

NOT Enhancer of

Statement

Reference

Scer\GAL4^tim.PU/tim^{UAS.L.Tag:FLAG} is a non-enhancer of abnormal locomotor rhythm | adult stage phenotype of per⁰¹

(Martin Anduaga et al., 2019)

Suppressor of

Statement

Reference

Scer\GAL4^tim.PU/tim^{UAS.sc.Tag:FLAG} is a suppressor of abnormal locomotor rhythm | adult stage phenotype of per⁰¹

(Martin Anduaga et al., 2019)

Scer\GAL4^tim.PU/per^UAS.cYa is a suppressor | partially of abnormal circadian rhythm | adult stage phenotype of Scer\GAL4^tim.PU, Sur-8^JF03236

(Xue et al., 2019)

NOT Suppressor of

Statement

Reference

Scer\GAL4^tim.PU/tim^{UAS.L.Tag:FLAG} is a non-suppressor of abnormal locomotor rhythm | adult stage phenotype of per⁰¹

(Martin Anduaga et al., 2019)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^tim.PU/CoRest^{UAS.ORF.GW.Tag:HA} rescues CoRest^EY14216

(Lv et al., 2024)

Scer\GAL4^tim.PU/CoRest^{UAS.ORF.GW.Tag:HA} rescues CoRest^MI08173

(Lv et al., 2024)

Scer\GAL4^tim.PU/nmo^UAS.cUa.GFP rescues nmo^P1/Df(3L)Exel6279

(Yu et al., 2011)

Partially rescues

Scer\GAL4^tim.PU/tim^{UAS.L.Tag:FLAG} partially rescues tim⁰¹

(Martin Anduaga et al., 2019)

Scer\GAL4^tim.PU/tim^{UAS.sc.Tag:FLAG} partially rescues tim⁰¹

(Martin Anduaga et al., 2019)

Fails to rescue

Scer\GAL4^tim.PU/CoRest^{UAS.C.Tag:MYC} fails to rescue CoRest^EY14216

(Lv et al., 2024)

Scer\GAL4^tim.PU/CoRest^{UAS.C.Tag:MYC} fails to rescue CoRest^MI08173

(Lv et al., 2024)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Scer\GAL4^tim.PU

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Unknown

Secondary FlyBase IDs

References (34)

Report Sections

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