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General Information
Symbol
Dmel\mora2
Species
D. melanogaster
Name
FlyBase ID
FBal0298313
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    Comment:

    A one base pair deletion GCCATT(G)AGGTG in codon E135 leads to a frameshift and early translation termination.

    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference

    A 1 bp deletion at codon 134 (between the two CHORD domains) that causes a frame-shift that results in a premature STOP codon at M172 in the 2nd CHORD domain.

    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Homozygous neurons (generated via a Scer\FLP1SOP / MARCM method) generate miniature (i.e. a proportionally scaled down microcopy of wild type) dendritic arbors regardless of body size/nutritional input: dendritic segment length is reduced without simplifying the branching pattern in both fed and starved flies.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Rescued by
    Comments

    P{CHORD4.8} almost fully rescues the miniature dendritic arbor phenotype seen in CHORD2 neurons.

    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer

    Isolated as a shared background mutation on the PBac{SAstopDsRed}LL04611 and PBac{SAstopDsRed}LL04133 chromosomes.

    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    Name Synonyms
    Secondary FlyBase IDs
      References (1)