FB2020_03, released Jun 16, 2020

Allele: Dmel\Fbxl7UAS.Tag:FLAG

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General Information
Symbol
Dmel\Fbxl7UAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0298386
Feature type
allele
Associated gene
Dmel\Fbxl7
Associated Insertion(s)
Carried in Construct
P{UAS-FLAG-Fbxl7}
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - regulatory fusion
(Bosch et al., 2014)
in vitro construct - coding region fusion
(Bosch et al., 2014)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Carried in construct
      P{UAS-FLAG-Fbxl7}
      Cytology
      Nature of the lesion
      Statement
      Reference

      UAS regulates expression of the coding sequence of Fbxl7 with an N-terminal Tag:FLAG tag.

      (Bosch et al., 2014)
      Allele components
      Product class / Tool use(s)
      Regulatory region(s)
      UAS
      Encoded product / tool
      Fbxl7
      Tagged with
      Tag:FLAG
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The wings of Fbxl7Scer\UAS.T:Zzzz\FLAG Scer\GAL4nub-AC-62 flies are smaller than wild-type wings, and the distance between the cross veins is reduced. The distal leg segments of these flies are also reduced in size.

      (Bosch et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Fbxl7UAS.Tag:FLAG, Scer\GAL4nub-AC-62 has wing phenotype, suppressible by wtsx1/wts[+]

      (Bosch et al., 2014)

      Fbxl7UAS.Tag:FLAG, Scer\GAL4nub-AC-62 has wing phenotype, suppressible by cindrPC.UAS.EGFP, Scer\GAL4nub-AC-62

      (Bosch et al., 2014)
      Suppressor of
      Statement
      Reference

      Scer\GAL4αTub84B.PL/Fbxl7UAS.Tag:FLAG is a suppressor of imaginal disc phenotype of ft8/ft61

      (Bosch et al., 2014)
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4αTub84B.PL/Fbxl7UAS.Tag:FLAG is a non-suppressor of imaginal disc phenotype of ft8/ftG-rv

      (Bosch et al., 2014)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Scer\GAL4αTub84B.PL-mediated expression of Fbxl7Scer\UAS.T:Zzzz\FLAG suppresses ft8/ft61, but not ft8/ftG-rv, phenotypes, resulting in viable flies.

      The increased size of dco3, but not wtsx1, clones is rescued by Fbxl7Scer\UAS.T:Zzzz\FLAG expression.

      (Bosch et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Fbxl7Scer\UAS.T:Zzzz\FLAG
      Fbxl7UAS.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)