FlyBase Allele Report: Dmel\slmb[UAS.vhhGFP4]

General Information

Symbol

Dmel\slmb^UAS.vhhGFP4

Species

D. melanogaster

Name

FlyBase ID

FBal0298957

Feature type

allele

Associated gene

Dmel\slmb

Associated Insertion(s)

Carried in Construct

M{UAS-Nslmb-vhhGFP4}

P{UAS-Nslmb-vhhGFP4}

Also Known As

deGradFP

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

in vitro construct - regulatory fusion

(Caussinus et al., 2011)

in vitro construct - coding region fusion

(Caussinus et al., 2011)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Carried in construct

M{UAS-Nslmb-vhhGFP4}

P{UAS-Nslmb-vhhGFP4}

Cytology

Nature of the lesion

Statement

Reference

UAS regulatory sequences drive expression of the first 198 amino acids residues of slmb which are tagged with vhhGFP4.

(Caussinus et al., 2011)

Allele components

Product class / Tool use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

slmb

Tagged with

vhhGFP4

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Phenotypic Data

Phenotypic Class

fertile, with Scer\GAL4^nullo.PG

(Caussinus et al., 2011)

fertile, with Scer\GAL4^Tub.PU

(Caussinus et al., 2011)

learning defective | heat sensitive, with Scer\GAL4^117Y, dnc^{MI03415-GFSTF.2}

(Nagarkar-Jaiswal et al., 2015)

lethal | heat sensitive, with Scer\GAL4^da.PU, brp^{MI02987-GFSTF.0}

(Nagarkar-Jaiswal et al., 2015)

lethal | heat sensitive, with Scer\GAL4^nSyb.PS, brp^{MI02987-GFSTF.0}

(Nagarkar-Jaiswal et al., 2015)

lethal - all die during embryonic stage | heat sensitive, with Scer\GAL4^Tub.PU, dlg1^{MI06353-GFSTF.0}

(Nagarkar-Jaiswal et al., 2015)

lethal - all die during embryonic stage | heat sensitive, with α-Cat^{MI02577-GFSTF.0}, Scer\GAL4^Act.PU

(Nagarkar-Jaiswal et al., 2015)

locomotor behavior defective | heat sensitive, with Scer\GAL4^nSyb.PS, brp^{MI02987-GFSTF.0}

(Nagarkar-Jaiswal et al., 2015)

memory defective | conditional, with Scer\GAL4^Mef2.247, meng^{MI03008-GFSTF.1}

(Lee et al., 2018)

neurophysiology defective, with Scer\GAL4^ey.PU, brp^{MI02987-GFSTF.0}

(Nagarkar-Jaiswal et al., 2015)

neurophysiology defective | heat sensitive, with Scer\GAL4^nSyb.PS, brp^{MI02987-GFSTF.0}

(Nagarkar-Jaiswal et al., 2015)

planar polarity defective, with Rab23^EYFP, Scer\GAL4^en.PU

(Dunst et al., 2015)

viable, with Scer\GAL4^nullo.PG

(Caussinus et al., 2011)

viable, with Scer\GAL4^Tub.PU

(Caussinus et al., 2011)

visible, with α-Cat^{MI02577-GFSTF.0}, Scer\GAL4^ey.PU

(Nagarkar-Jaiswal et al., 2015)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

sqh^AX3 embryos which carry sqh^{RLC.T:Avic\GFP-S65T} and which also express slmb^{Scer\UAS.T:Zzzz\vhhGFP4} under the control of Scer\GAL4^332.3 in the postmitotic amnioserosa cells show a dorsal open phenotype. Df(2R)BSC696 flies carrying ap^{KI.T:Avic\GFP} and also expressing slmb^{Scer\UAS.T:Zzzz\vhhGFP4} under the control of Scer\GAL4^tub.PU have wing defects.

(Caussinus et al., 2011)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (6)

Bloomington

38421

w^*; P{UAS-Nslmb-vhhGFP4}3

38422

y¹ w^*; P{UAS-Nslmb-vhhGFP4}2