Open Close
General Information
Symbol
Dmel\mir-bansponge.UAS.DsRed(Unk)
Species
D. melanogaster
Name
FlyBase ID
FBal0299697
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-bantamsponge, UAS-bantam sponge
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference
UASt regulatory sequences drive expression of the DsRed(Unk) coding sequence upstream of a sequence containing ten binding sites that are complementary to the mature ban sequence and a central bulge.
Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
The expression of bansponge.UAS.DsRed(Unk) under the triple control of Scer\GAL4VP16.nos.UTR, Scer\GAL4nos.PG and Scer\GAL4VP16.otu leads to a significant decrease in germline stem cells (GSCs) per germarium, with the occurrence of some germaria with no GSCs, as compared to controls; this effect is more pronounced under starvation then under standard nutrition.
Secondary neuroblasts in larval brains expressing bansponge.Scer\UAS.T:Disc\RFP under the control of Scer\GAL4insc-Mz1407 show a significant decrease in nucleolar size, as compared to wild type.
Scer\GAL4Mef2.PU-mediated expression results in a progressive, age-dependent loss of flight resulting in a penetrant flightless phenotype at 30 days post eclosion. Indirect flight muscle myofibril structure shows marked defects in integrity and sarcomere organization.
Expression of bansponge.Scer\UAS.T:Disc\RFP under the control of Scer\GAL4esg-NP5130 reduces the number of midgut precursor cells compared to controls. The increase in midgut precursor cells seen in flies treated with dextran sulfate sodium (DSS) is reversed upon expression of bansponge.Scer\UAS.T:Disc\RFP in the precursor cells under the control of Scer\GAL4esg-NP5130.
Expressing mir-bansponge.UAS.DsRed(Unk) under the control of Scer\GAL4Bx-MS1096 results in a significantly smaller wing compared to wild-type controls.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Enhanced by
Suppressed by
NOT suppressed by
Suppressor of
NOT Suppressor of
Statement
Reference
Phenotype Manifest In
NOT Enhanced by
Suppressed by
NOT suppressed by
Suppressor of
NOT Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference
Co-expression of bansponge.Scer\UAS.T:Disc\RFP suppresses the disrupted A1 epithelial folding and cell mixing at the A1 field boundary seen in eye-antennal discs expressing NECN.Scer\UAS.cGa under the control of Scer\GAL4hth-GETDB.
Co-expression of CycEScer\UAS.cLa fails to suppress the decreased nucleolar size phenotype seen in secondary neuroblasts in larval brains expressing bansponge.Scer\UAS.T:Disc\RFP under the control of Scer\GAL4insc-Mz1407. Co-expression of bansponge.Scer\UAS.T:Disc\RFP (but not of both bansponge.Scer\UAS.T:Disc\RFP and numbHMS01459, or both bansponge.Scer\UAS.T:Disc\RFP and MycScer\UAS.cZa, or both bansponge.Scer\UAS.T:Disc\RFP and CG8184HMS01605 or a combination of expression of bansponge.Scer\UAS.T:Disc\RFP and the presence of numb15/+) leads to partial suppression of the ectopic neuroblast formation and increased neuroblast numbers seen in larval brains expressing NScer\UAS.T:SV5\V5,T:Zzzz\His6 under the control of Scer\GAL4insc-Mz1407. Co-expression of bansponge.Scer\UAS.T:Disc\RFP leads to partial suppression of the increased neuroblast numbers seen in larval brains expressing dpnScer\UAS.cSa under the control of Scer\GAL4insc-Mz1407. Co-expression of bansponge.Scer\UAS.T:Disc\RFP fails to suppress the increased nucleolar size seen in secondary neuroblasts of larval brains expressing numbHMS01459 under the control of Scer\GAL4insc-Mz1407. Co-expression of bansponge.Scer\UAS.T:Disc\RFP suppresses the ectopic type II neuroblast phenotype seen in larval brain clones expressing numbTS4D.Scer\UAS under the control of Scer\GAL4Act.PU.
Expression of bansponge.Scer\UAS.T:Disc\RFP does not suppress the increase in intestinal stem cell division when Ras85DG12V.Scer\UAS.cLa is expressed under the control of Scer\GAL4esg-NP5130 (restricted to the adult stages using Scer\GAL80ts.αTub84B). Expression of bansponge.Scer\UAS.T:Disc\RFP does not suppress the tumor-like intestinal stem cell accumulation seen when NHMS00001 is expressed under the control of Scer\GAL4esg-NP5130 (restricted to the adult stages using Scer\GAL80ts.αTub84B). Expression of bansponge.Scer\UAS.T:Disc\RFP does not suppress the increase in intestinal stem cell division when ykiScer\UAS.cZa is expressed in enterocytes (ECs) under the control of Scer\GAL4Myo31DF-NP0001 (restricted to the adult stages using Scer\GAL80ts.αTub84B). Expression of bansponge.Scer\UAS.T:Disc\RFP suppresses the increase in intestinal stem cell division seen when ykiScer\UAS.cZa is expressed under the control of Scer\GAL4esg-NP5130 (restricted to the adult stages using Scer\GAL80ts.αTub84B). Expression of bansponge.Scer\UAS.T:Disc\RFP does not suppress the increase in intestinal stem cell division when Egfr1.Scer\UAS is expressed under the control of Scer\GAL4esg-NP5130 (restricted to the adult stages using Scer\GAL80ts.αTub84B). Expression of bansponge.Scer\UAS.T:Disc\RFP suppresses the increase in intestinal stem cell division in savSH8 mutant clones.
Expression of bansponge.Scer\UAS.T:Disc\RFP largely rescues the dorsal-ventral boundary defects seen when NdsRNA.P.Scer\UAS is expressed under the control of Scer\GAL4vg.int2.1.
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (5)
Reported As
Symbol Synonym
Disc\RFPdsRed.Scer\UAS.ban-sponge
bansponge.Scer\UAS.T:Disc\RFP
bansponge.UAS.DsRed(Unk)
mir-bansponge.UAS.DsRed(Unk)
Name Synonyms
Secondary FlyBase IDs
  • FBal0270089
References (11)