Open Close
General Information
Symbol
Dmel\PAPLA1Δ1682-1686
Species
D. melanogaster
Name
FlyBase ID
FBal0299769
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
deletion
Comment:

Deletion of 5 amino acids (GHSLG) in the enzyme active site created on 31 kb PAPLA1 rescue genomic fragment by site-directed mutagenesis.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A 31-kb genomic fragment modified to carry an active site mutation in PAPLA1. The residues corresponding to the sequence GHSLG at 1682-1686 in the PAPLA1 polypeptide are deleted.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to rescue
Comments

Transgenic lines encoding PAPLA1Δ1682-1686 fail to rescue the male sterile phenotype of PAPLA1KO.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
PAPLA1Δ1682-1686
Name Synonyms
Secondary FlyBase IDs
    References (1)