FB2021_01, released Feb 18, 2021

Allele: Dmel\mir-10KO

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General Information
Symbol
Dmel\mir-10KO
Species
D. melanogaster
Name
FlyBase ID
FBal0301887
Feature type
allele
Associated gene
Dmel\mir-10
Associated Insertion(s)
TI{GAL4}mir-10KO
Carried in Construct
Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Chen et al., 2014)
Mutagen
ends-out gene targeting
(Chen et al., 2014)
FLPase
(Chen et al., 2014)
I-SceI
(Chen et al., 2014)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Cytology
      Nature of the lesion
      Statement
      Reference

      The mir-10 hairpin has been deleted and replaced by sequence encoding the Scer\GAL4 coding region plus a loxP cassette containing the w+mW.hs marker.

      (Chen et al., 2014)
      Insertion components
      TI{GAL4}mir-10KO
      Product class / Tool use(s)
      Encoded product / tool
      GAL4
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Embryos derived from mir-10KO/Df(3R)BSC467 embryos show a significant decrease in the number of primordial germ cells compared to embryos from control females.

      (Chen et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      mir-10KO
      (Hanyu-Nakamura et al., 2019, Niu et al., 2019)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)