FlyBase Allele Report: Dmel\mir-317[KO]

General Information

Symbol

Dmel\mir-317^KO

Species

D. melanogaster

Name

FlyBase ID

FBal0301922

Feature type

allele

Associated gene

Dmel\mir-317

Associated Insertion(s)

TI{TI}mir-317^KO

Carried in Construct

Allele class

amorphic allele - molecular evidence

Mutagen

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Chen et al., 2014)

Mutagen

ends-out gene targeting

(Chen et al., 2014)

FLPase

(Chen et al., 2014)

I-SceI

(Chen et al., 2014)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Cytology

Nature of the lesion

Statement

Reference

The mir-317 hairpin has been deleted. A w^+mW.hs marker which is flanked firstly by a pair of loxP sites and secondly (flanking the loxP sites) by a pair of inverted attP sites is present in place of the deleted sequence.

(Chen et al., 2014)

Insertion components

TI{TI}mir-317^KO

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Phenotypic Data

Phenotypic Class

female fertile

(Chen et al., 2014)

male fertile

(Chen et al., 2014)

short lived | female (with Df(3R)BSC526)

(Chen et al., 2014)

short lived | female | recessive

(Chen et al., 2014)

short lived | male (with Df(3R)BSC526)

(Chen et al., 2014)

short lived | male | recessive

(Chen et al., 2014)

viable

(Chen et al., 2014)

Phenotype Manifest In

Detailed Description

Statement

Reference

Homozygous males and females show a significant decrease in median lifespan compared to controls.

mir-317^KO/Df(3R)BSC526 males and females show a significant decrease in median lifespan compared to controls.

(Chen et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

58926

w^*; TI{TI}mir-317^KO/TM3, Sb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

miR-317 KO

(Iftikhar et al., 2019)

mir-317^KO

(Niu et al., 2019)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

Open Close