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General Information
Symbol
Dmel\tut1
Species
D. melanogaster
Name
FlyBase ID
FBal0302043
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

C8210028T

Reported nucleotide change:

 :G8203128A

Amino acid change:

Q175term | tut-PA

Reported amino acid change:

?175term

Comment:

The reported nucleotide change was for the negative strand.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Nucleotide substitution: G8203128A.

Amino acid replacement: ?175term.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Mutants exhibit germ cell overgrowth - male germ cells arrest at the spermatogonial transit-amplifying stage and over-proliferate. The testis lacks later germ cells such as spermatocytes.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

Scer\GAL4nos.PU-mediated expression of bamScer\UAS.P\T.T:Avic\GFP in a tut1/tut3 background results in a tut mutant phenotype.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Not rescued by
Comments

Scer\GAL4bam.T:Hsim\VP16-mediated expression, but not Scer\GAL4tj.PU-mediated expression of tutScer\UAS.T:Avic\GFP rescues the testis phenotype of tut1/tut3.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)