Q175term | tut-PA
The reported nucleotide change was for the negative strand.
Nucleotide substitution: G8203128A.
Amino acid replacement: ?175term.
increased cell number
increased cell number (with tut3)
spermatogonium (with tut3)
testis (with tut3)
Mutants exhibit germ cell overgrowth - male germ cells arrest at the spermatogonial transit-amplifying stage and over-proliferate. The testis lacks later germ cells such as spermatocytes.
tut1/tut3 is a suppressor of male germline stem cell phenotype of Scer\GAL4nos.PU, bamUASp.GFP
Scer\GAL4nos.PU-mediated expression of bamScer\UAS.P\T.T:Avic\GFP in a tut1/tut3 background results in a tut mutant phenotype.
tut1/tut3 is rescued by tutUAS.GFP/Scer\GAL4VP16.bam
tut1/tut3 is not rescued by tutUAS.GFP/Scer\GAL4tj.PU
Scer\GAL4bam.T:Hsim\VP16-mediated expression, but not Scer\GAL4tj.PU-mediated expression of tutScer\UAS.T:Avic\GFP rescues the testis phenotype of tut1/tut3.