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General Information
Symbol
Dmel\NAT1GS2099
Species
D. melanogaster
Name
FlyBase ID
FBal0302231
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Mutagen
    Nature of the Allele
    Mutagen
    Mutations Mapped to the Genome
     
    Type
    Location
    Additional Notes
    References
    transposable element insertion site
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
     
    Progenitor genotype
    Cytology
    Nature of the lesion
    Statement
    Reference

    Insertion in exon 3 (coding region) resulting in the truncation of the NAT1 protein just after amino acid 850 and deletion of almost the entire W2 domain.

    Insertion components
    P{GSV1}GS2099
    Product class / Tool use(s)
    Encoded product / tool
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    NAT1GS2099 embryos begin germband extension at approximately the correct time, but extension stops abruptly and the germband retracts. Mutants also exhibit an abnormally deep cephalic furrow. Mutants are able to form an embryonic cuticle, though they show a reduction in ventral cuticle bands.

    External Data
    Interactions
    Show genetic interaction network for Enhancers & Suppressors
    Phenotypic Class
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference
    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Rescued by
    Comments

    NAT1+t12.6 completely rescues the lethality associated with NAT1GS2099.

    Images (0)
    Mutant
    Wild-type
    Stocks (1)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (2)
    Reported As
    Symbol Synonym
    NAT1GS2099
    Name Synonyms
    Secondary FlyBase IDs
      References (1)