FB2025_01 , released February 20, 2025
Allele: Dmel\mir-31aUAS.cSb
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General Information
Symbol
Dmel\mir-31aUAS.cSb
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct b of Szuplewski
FlyBase ID
FBal0304029
Feature type
allele
Associated gene
Dmel\mir-31a
Associated Insertion(s)
Carried in Construct
P{UAS-mir-31a.S}
PBac{UAS-mir-31a.S}
Key Links
Transgenic product class
wild_type
(Szuplewski et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Szuplewski et al., 2012)
Mutagen
in vitro construct
(Szuplewski et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-mir-31a.S}
PBac{UAS-mir-31a.S}
Cytology
Description

UAS regulatory sequences drive expression of a genomic fragment containing the mir-31a miRNA stem loop plus approximately 100bp upstream and downstream.

(Szuplewski et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
mir-31a
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Statement
      Reference

      mir-31aUAS.cSb/Scer\GAL4sca.PU is a non-suppressor of visible phenotype of Scer\GAL4sca.PU, miGD11624

      (Szuplewski et al., 2012)
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      mir-31aUAS.cSb/Scer\GAL4sca.PU is a non-suppressor of macrochaeta phenotype of Scer\GAL4sca.PU, miGD11624

      (Szuplewski et al., 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4insc-Mz1407/mir-31aUAS.cSb rescues mir-31aKO

      (Foo et al., 2017)

      Scer\GAL4mir-31a/mir-31aUAS.cSb rescues mir-31aKO.Gal4

      (Foo et al., 2017)
      Comments

      Expressing mir-31aScer\UAS.cSb under the control of either Scer\GAL4insc-Mz1407 or Scer\GAL4mir-31a (the intrinsic Gal4 driver of mir-31aKO.Gal4) rescues the decreased number of adult brain glial cells present in 7 days old mir-31aKO homozygotes or mir-31aKO.Gal4 homozygotes, respectively.

      (Foo et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      mir-31aScer\UAS.cSb
      mir-31aUAS.cSb
      Name Synonyms
      Saccharomyces cerevisiae UAS construct b of Szuplewski
      Secondary FlyBase IDs
        References (3)