TrpA1ins flies show lack of defecation in response to uracil or N-methylmaleimide.
Guts from TrpA1ins flies exhibit increased colony-forming units 5 hours after feeding with the microbe Erwinia carotovora.
When fed wild-type Erwinia carotovora, TrpA1ins flies display no change in mortality rate as compared to control flies.
TrpA1ins mutants exhibit normal light-dependent temperature preference. Similarly to wild-type, they prefer higher temperature in the light than in the dark.
TrpA1ins mutant adults have significantly reduced aversive temperature, but not shock, olfactory memory, compared to controls.
TrpA1ins/TrpA1ins does not significantly affect locomotor turning frequency in third instar larvae.
TrpA1ins mutant flies show complete loss of the long term thermal preference (response to a shallow temperature gradient after 30 min) seen in wild type flies. The flies show a preference for temperatures >28[o]C.
Berberine-sensitive i-type taste bristles in the labellum do not respond to N-methylmaleimide in an extracellular tip recording assay in TrpA1ins flies (in contrast to wild type where robust spiking is induced). Warming to 39[o]C does not elicit spiking in these cells, both in mutant and wild-type flies.
TrpA1ins flies show decreased avoidance of food containing N-methylmaleimide compared to wild type.
Homozygous mutants fail to avoid noxious temperature levels. There is no difference in temperature-induced paralysis between TrpA1ins and wild-type flies subjected to 46[o]C. Mutant flies do not exhibit any coordination defects.
TrpA1ins flies display a reduced aversion to aristolochic acid compared to wild type.
In contrast to wild type, TrpA1ins flies have virtually no aristolochic acid-induced action potentials in tip recordings of sensillum s6.
TrpA1ins flies show greatly reduced avoidance of 1% citronellal in a direct airborne repellent test (DART) assay.
TrpA1ins flies show an altered distribution along a thermal gradient compared to wild-type flies. The mutant flies show increased accumulation in the warmest regions (28-32[o]C) of the gradient, but not in the coolest region (18-22[o]C).
TrpA1ins/Df(3L)ED4415 flies show an altered distribution along a thermal gradient compared to wild-type flies. The mutant flies show increased accumulation in the warmest regions (28-32[o]C) of the gradient, but not in the coolest region (18-22[o]C).
Anterior cell (AC) neurons in the brains of TrpA1ins flies do not show warmth-responsive increases in intracellular calcium, in contrast to control AC neurons.