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General Information
Symbol
Dmel\Su(var)3-714
Species
D. melanogaster
Name
FlyBase ID
FBal0304387
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Duplication at the Su(var)3-7 locus, with each copy of the gene separated by a y+2083 marker. The 5' copy is a fusion protein containing a wild-type copy of Su(var)3-7 fused at its C-terminus in frame with 157 amino acids of the y protein (this structure is due to the cloning procedure used to make the donor construct). The 3' copy contains a 3.7kb deletion which removes most of the Su(var)3-7 gene.

Insertion components
TI{TI}Su(var)3-714
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Su(var)3-714/+ does not significantly affect the size of the adult eye, as compared to wild type.

The X chromosome is shorter than normal and bloated in polytene chromosome squashes from male homozygous Su(var)3-714 third instar larvae.

The chromocenter has slightly loose morphology in polytene chromosome squashes from homozygous Su(var)3-714 third instar larvae.

The chromocenter has loose morphology in polytene chromosome squashes from Su(var)3-714/Su(var)3-79 third instar larvae.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
NOT Suppressor of
Statement
Reference

Su(var)3-714/Su(var)3-7[+] is a non-suppressor of size defective | adult stage phenotype of Scer\GAL4ey.PU, Trl519.UAS

Other
Phenotype Manifest In
Suppressed by
Statement
Reference
NOT Suppressor of
Statement
Reference

Su(var)3-714/Su(var)3-7[+] is a non-suppressor of eye | adult stage phenotype of Scer\GAL4ey.PU, Trl519.UAS

Additional Comments
Genetic Interactions
Statement
Reference

Su(var)3-714/+ fails to restore the eye size of flies expressing Trl519.Scer\UAS under the control of Scer\GAL4dpp.PU.

Homozygosity for mle1 suppresses the bloated X chromosome phenotype seen in polytene chromosome squashes from male homozygous Su(var)3-714 third instar larvae.

When P{P-Sal}Pak3P-Sal is present, the w gene of the P{lacW}ciDplac insertion variegates, resulting (in a w[-] background) in an eye that is mostly white with a few patches of red ommatidia. This P-element-dependent silencing of P{lacW}ciDplac is dominantly suppressed by Su(var)3-714.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescued by
Comments

Loss of maternal and zygotic Su(var)3-7 is lethal.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
Dp(3;3)Su(var)3-714
Su(var)3-714.3'
Su(var)3-714.5'
Name Synonyms
Secondary FlyBase IDs
  • FBal0147399
  • FBal0147398
  • FBab0037617
References (5)