Open Close
General Information
Symbol
Dmel\α-CatMI02577-GFSTF.0
Species
D. melanogaster
Name
FlyBase ID
FBal0304660
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference
The RMCE cassette of the Mi{MIC}α-CatMI02577 insertion has been replaced with a EGFP-FlAsH-StrepII-TEV-3xFlag multi-tag cassette. The insertion is in a coding intron of α-Cat and is predicted to protein trap the gene.
Insertion components
Mi{PT-GFSTF.0}α-CatMI02577-GFSTF.0
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
α-CatMI02577-GFSTF.0 flies in which the level of α-Cat protein has been reduced by expressing slmbScer\UAS.T:Zzzz\vhhGFP4 (which targets GFP-tagged proteins for degradation) under the control of Scer\GAL4Act.PU are viable at 18[o]C, but show embryonic lethality at 28[o]C. α-CatMI02577-GFSTF.0 flies in which the level of α-Cat protein has been reduced by expressing slmbScer\UAS.T:Zzzz\vhhGFP4 under the control of Scer\GAL4ey.PU have a rough eye phenotype at 28[o]C. α-CatMI02577-GFSTF.0 flies in which the level of α-Cat protein has been reduced in the eye (by using Scer\GAL4ey.PU to express an RNAi construct which targets the GFP sequence-containing mRNA for degradation) have small, rough eyes at 28[o]C.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
α-Cat-EGFP-α-Cat
α-CatMI02577-GFSTF.0
Name Synonyms
Secondary FlyBase IDs
    References (3)