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General Information
Symbol
Dmel\dlg1MI06353-GFSTF.0
Species
D. melanogaster
Name
FlyBase ID
FBal0304667
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Cytology
Nature of the lesion
Statement
Reference
The RMCE cassette of the Mi{MIC}dlg1MI06353 insertion has been replaced with a EGFP-FlAsH-StrepII-TEV-3xFlag multi-tag cassette. The insertion is in a coding intron of dlg1 and is predicted to protein trap the gene.
Insertion components
Mi{PT-GFSTF.0}dlg1MI06353-GFSTF.0
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
dlg1MI06353-GFSTF.0 flies in which the level of dlg1 protein has been reduced by expressing slmbScer\UAS.T:Zzzz\vhhGFP4 (which targets GFP-tagged proteins for degradation) under the control of Scer\GAL4tub.PU develop normally and eclose without obvious phenotype at 18[o]C, but show embryonic lethality when raised continuously at 28[o]C. Animals which are shifted to 28[o]C during the first or second larval instar show hyperproliferation of the imaginal disc and brain as third instar larvae and show a mild decrease in neuromuscular junction growth (in terms of bouton number and synapse complexity). Animals which are shifted to 28[o]C during the first larval instar show defects in cell morphology and organisation in the larval midgut.
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
dlg1MI06353-GFSTF.0
Name Synonyms
Secondary FlyBase IDs
    References (3)