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General Information
Symbol
Scer\GAL4Dh44.PU
Species
S. cerevisiae
Name
Diuretic hormone 44 promoter construct of Unknown
FlyBase ID
FBal0305287
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Dh44-Gal4
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Dh44 regulatory sequences control expression of a GAL4 driver.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Artificial inactivation of DH44-positive neurons by the expression of Hsap\KCNJ2UAS.EGFP under the control of Scer\GAL4Dh44.PU abolishes the increased food consumptions induced by either dietary amino acids or dietary yeast extract observed in controls, but does not have an effect on baseline level of sucrose consumption; acute inactivation by the additional control of Gal80[ts] also abolishes the increased food consumptions induced by dietary amino acids.

Artificial activation of DH44-positive neurons by the expression of Bhal\NaChBacUAS.cNa under the control of Scer\GAL4Dh44.PU significantly enhances sucrose consumption, compared to controls. In the presence of dietary amino acids or yeast extract, this activation does not further increase food consumption.

Optogenetic activation (using Crei\ChR1::Vcar\ChR1::Vcar\ChR2ReaChR.UAS.Citrine with orange light) of the combined set of Scer\GAL4Gr28b.b.4.7 and Scer\GAL4Dh44.PU cells, but not Scer\GAL4Dh44.PU cells alone, in adults significantly increases food intake of satiated flies, compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
Scer\GAL4Dh44.PU
Name Synonyms
Diuretic hormone 44 promoter construct of Unknown
Secondary FlyBase IDs
    References (6)