FlyBase Allele Report: Dmel\Diap1[RNAi.UAS.cLa]

General Information

Symbol

Dmel\Diap1^RNAi.UAS.cLa

Species

D. melanogaster

Name

FlyBase ID

FBal0314150

Feature type

allele

Associated gene

Dmel\Diap1

Associated Insertion(s)

Carried in Construct

P{UAS-Diap1.RNAi.L}

Also Known As

UAS-DIAP1-RNAi, UAS-diap1-IR

Key Links

Transgenic product class

RNAi_reagent

(Leulier et al., 2006)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Leulier et al., 2006)

Mutagen

in vitro construct

(Arya and Lakhotia, 2008, Leulier et al., 2006)

Progenitor genotype

Carried in construct

P{UAS-Diap1.RNAi.L}

Cytology

Description

UAS regulatory sequences drive expression of an inverted repeat of a fragment of Diap1.

(Leulier et al., 2006)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

Diap1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal eye color, with Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

abnormal eye color, with Scer\GAL4^GMR.PFa

(Sinenko, 2017)

abnormal size | adult stage, with Scer\GAL4^GMR.PFa

(Sinenko, 2017)

increased cell death, with Scer\GAL4^{VP16.nanos.UTR}

(Yacobi-Sharon et al., 2013)

increased cell death | third instar larval stage, with Scer\GAL4^ap-md544

(Umemori et al., 2009)

increased cell death | third instar larval stage, with Scer\GAL4^GMR.PF

(Leulier et al., 2006)

lethal - all die before end of pupal stage, with Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

some die during pupal stage, with Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

visible, with Scer\GAL4^GMR.PF

(Arya and Lakhotia, 2008, Leulier et al., 2006)

visible | adult stage, with Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009, Arya and Lakhotia, 2008, Ribeiro et al., 2007, Leulier et al., 2006)

eye, with Scer\GAL4^GMR.PFa

(Sinenko, 2017)

eye disc | third instar larval stage, with Scer\GAL4^GMR.PF

(Leulier et al., 2006)

interommatidial bristle, with Scer\GAL4^GMR.PF

(Leulier et al., 2006)

male germline cell, with Scer\GAL4^{VP16.nanos.UTR}

(Yacobi-Sharon et al., 2013)

pigment cell, with Scer\GAL4^GMR.PF

(Arya and Lakhotia, 2008)

spermatogonial cyst, with Scer\GAL4^{VP16.nanos.UTR}

(Yacobi-Sharon et al., 2013)

wing disc | third instar larval stage, with Scer\GAL4^ap-md544

(Umemori et al., 2009)

Detailed Description

Statement

Reference

Expression of Diap1^{dsRNA.UAS.cLa} under the control of Scer\GAL4^GMR.PFa results in significant eye size reduction and depigmentation.

(Sinenko, 2017)

Male flies expressing th^{dsRNA.Scer\UAS.cLb} under the control of Scer\GAL4^{nos.UTR.T:Hsim\VP16} exhibit slightly increased levels of spermatogonial cyst death compared to controls.

(Yacobi-Sharon et al., 2013)

Scer\GAL4^GMR.PF-mediated expression of th^{dsRNA.Scer\UAS.cLa} induces massive degeneration reflected in disrupted pigmentation and reduction and roughening of the eye.

Approximately 5% of Scer\GAL4^GMR.PF,th^{dsRNA.Scer\UAS.cLa} animals die as pupae.

(Mallik and Lakhotia, 2009)

Compared with wild-type, third instar larvae expressing th^{dsRNA.Scer\UAS.cLb} under the control of Scer\GAL4^ap-md544 display signs of increased apoptosis in the dorsal compartment of wing imaginal discs.

(Umemori et al., 2009)

Expression of th^{dsRNA.Scer\UAS.cLa} under the control of Scer\GAL4^GMR.PF results in reduced, deformed and partially depigmented eyes.

(Arya and Lakhotia, 2008)

Expression of th^{dsRNA.Scer\UAS.cLb} under the control of Scer\GAL4^GMR.PF results in a small eye phenotype.

(Ribeiro et al., 2007)

Expression of th^{dsRNA.Scer\UAS.cLb} in the eye under the control of Scer\GAL4^GMR.PF results in massive cell death in third instar larval eye discs and severely deformed adult eyes. Adult eyes show a spotted-eye phenotype, distorted outer eye morphology, and no defined interior eye structures develop. Death of eye pigment cells occurs, and loss of eye bristles.

(Leulier et al., 2006)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has lethal | pupal stage phenotype, enhanceable by w^unspecified/w^unspecified

(Mallik and Lakhotia, 2009)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Hsp60D^UAS.cAa, Scer\GAL4^GMR.PF

(Arya and Lakhotia, 2008)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has increased cell death phenotype, enhanceable by Df(3L)H99/Df(3L)H99

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Strica^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Dredd^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

NOT Enhanced by

Statement

Reference

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has lethal | pupal stage phenotype, non-enhanceable by lncRNA:Hsrω^EP3037, Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has visible phenotype, non-enhanceable by puc^UAS.cMa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Suppressed by

Statement

Reference

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PFa has visible | adult stage phenotype, suppressible | partially by Usp15-31^KK101035, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PFa has abnormal eye color phenotype, suppressible | partially by Usp15-31^KK101035, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PFa has abnormal size | adult stage phenotype, suppressible | partially by Usp15-31^KK101035, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PFa has visible | adult stage phenotype, suppressible | partially by Usp15-31^KG04149/Usp15-31[+]

(Sinenko, 2017)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PFa has abnormal eye color phenotype, suppressible | partially by Usp15-31^KG04149/Usp15-31[+]

(Sinenko, 2017)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PFa has abnormal size | adult stage phenotype, suppressible | partially by Usp15-31^KG04149/Usp15-31[+]

(Sinenko, 2017)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PFa has visible | adult stage phenotype, suppressible | partially by Dark^KK104215, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PFa has abnormal eye color phenotype, suppressible | partially by Dark^KK104215, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PFa has abnormal size | adult stage phenotype, suppressible | partially by Dark^KK104215, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has lethal | pupal stage phenotype, suppressible by lncRNA:Hsrω^RNAi.Sym.UAS, Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has lethal | pupal stage phenotype, suppressible by lncRNA:Hsrω^EP93D, Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

Diap1^RNAi.UAS.cLa, Drice^RNAi.UAS.cLb, Scer\GAL4^GMR.PF has visible phenotype, suppressible | partially by Dcp-1^RNAi.UAS.cLa/Decay^RNAi.UAS.cLa/Damm^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by Dronc^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by Dark^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by Drice^RNAi.UAS.cLb, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by Diap2^GMR.PH, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has increased cell death phenotype, suppressible by Diap2^GMR.PH, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by Dronc^I29/Dronc^I29

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has visible phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has increased cell death phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

NOT suppressed by

Statement

Reference

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has lethal | pupal stage phenotype, non-suppressible by lncRNA:Hsrω^EP3037, Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by Hsp60D^RNAi.Sym.UAS, Scer\GAL4^GMR.PF

(Arya and Lakhotia, 2008)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by puc^UAS.cMa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by Df(3L)H99/Df(3L)H99

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by Dcp-1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has increased cell death phenotype, non-suppressible by Decay^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has increased cell death phenotype, non-suppressible by Damm^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has visible phenotype, non-suppressible by Fadd^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Phenotype Manifest In

Enhanced by

Statement

Reference

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by w^unspecified/w^unspecified

(Mallik and Lakhotia, 2009)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by lncRNA:Hsrω^EP93D, Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by lncRNA:Hsrω^EP3037, Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Hsp60D^UAS.cAa, Scer\GAL4^GMR.PF

(Arya and Lakhotia, 2008)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Strica^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Dredd^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

NOT Enhanced by

Statement

Reference

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, non-enhanceable by puc^UAS.cMa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Suppressed by

Statement

Reference

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PFa has eye phenotype, suppressible | partially by Usp15-31^KK101035, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PFa has eye phenotype, suppressible | partially by Usp15-31^KG04149/Usp15-31[+]

(Sinenko, 2017)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PFa has eye phenotype, suppressible | partially by Dark^KK104215, Scer\GAL4^GMR.PFa

(Sinenko, 2017)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by lncRNA:Hsrω^RNAi.Sym.UAS, Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

Diap1^RNAi.UAS.cLa has eye phenotype, suppressible by Scer\GAL4^GMR.PF/Diap2^UAS.cLa

(Ribeiro et al., 2007)

Diap1^RNAi.UAS.cLa has eye phenotype, suppressible by Diap2^C46G.UAS/Scer\GAL4^GMR.PF

(Ribeiro et al., 2007)

Diap1^RNAi.UAS.cLa has eye phenotype, suppressible by Scer\GAL4^GMR.PF/Diap2^C149G.UAS

(Ribeiro et al., 2007)

Diap1^RNAi.UAS.cLa, Drice^RNAi.UAS.cLb, Scer\GAL4^GMR.PF has eye phenotype, suppressible | partially by Dcp-1^RNAi.UAS.cLa/Decay^RNAi.UAS.cLa/Damm^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by Dronc^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by Dark^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by Drice^RNAi.UAS.cLb, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by Diap2^GMR.PH, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by Dronc^I29/Dronc^I29

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has interommatidial bristle phenotype, suppressible by Dronc^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has interommatidial bristle phenotype, suppressible by Dronc^I29/Dronc^I29

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has interommatidial bristle phenotype, suppressible by Dark^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, suppressible by BacA\p35^UAS.cHa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

NOT suppressed by

Statement

Reference

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF, rpr^GMR.PW has eye phenotype, non-suppressible by lncRNA:Hsrω^RNAi.Sym.UAS, Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF, grim^GMR.PH has eye phenotype, non-suppressible by lncRNA:Hsrω^RNAi.Sym.UAS, Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF, egr^UAS.cIa has eye phenotype, non-suppressible by lncRNA:Hsrω^RNAi.Sym.UAS, Scer\GAL4^GMR.PF

(Mallik and Lakhotia, 2009)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Hsp60D^RNAi.Sym.UAS, Scer\GAL4^GMR.PF

(Arya and Lakhotia, 2008)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has pigment cell phenotype, non-suppressible by Hsp60D^RNAi.Sym.UAS, Scer\GAL4^GMR.PF

(Arya and Lakhotia, 2008)

Diap1^RNAi.UAS.cLa has eye phenotype, non-suppressible by Diap2^C249G.UAS/Scer\GAL4^GMR.PF

(Ribeiro et al., 2007)

Diap1^RNAi.UAS.cLa has eye phenotype, non-suppressible by Diap2^C466Y.UAS/Scer\GAL4^GMR.PF

(Ribeiro et al., 2007)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Dcp-1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Fadd^RNAi.UAS.cLa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has interommatidial bristle phenotype, non-suppressible by Diap2^GMR.PH, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has interommatidial bristle phenotype, non-suppressible by Drice^RNAi.UAS.cLb, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has interommatidial bristle phenotype, non-suppressible by BacA\p35^UAS.cHa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by puc^UAS.cMa, Scer\GAL4^GMR.PF

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by hid⁰⁵⁰¹⁴/Df(3L)H99

(Leulier et al., 2006)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF has eye phenotype, non-suppressible by Df(3L)H99/Df(3L)H99

(Leulier et al., 2006)

Enhancer of

Statement

Reference

Diap1^RNAi.UAS.cLa/Scer\GAL4^GMR.PF is an enhancer of eye phenotype of rpr^GMR.PW

(Mallik and Lakhotia, 2009)

Diap1^RNAi.UAS.cLa/Scer\GAL4^GMR.PF is an enhancer of eye phenotype of grim^GMR.PH

(Mallik and Lakhotia, 2009)

Diap1^RNAi.UAS.cLa, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, egr^UAS.cIa

(Mallik and Lakhotia, 2009)

Additional Comments

Genetic Interactions

Statement

Reference

The eye phenotype (depigmentation and size reduction) characteristic for flies expressing Diap1^{dsRNA.UAS.cLa} under the control of Scer\GAL4^GMR.PFa is slightly improved by co-expression of Usp15-31^KK101035 or by combination with a single copy of Usp15-31^KG04149 and is strongly suppressed by co-expression of Dark^KK104215.

(Sinenko, 2017)

Scer\GAL4^GMR.PF-mediated expression of th^{dsRNA.Scer\UAS.cLa} results in a more severe eye phenotype and increased pupal lethality in a homozygous w^unspecified background compared to a w^unspecified/+ background.

Expression of P{Sym-UAS-Hsrω} leads to recovery of eye size and morphology in Scer\GAL4^GMR.PF,th^{dsRNA.Scer\UAS.cLa} flies, though the ommatidial lattice is still disrupted. Pupal lethality is also suppressed.

Co-expression of Hsrω^EP93D or Hsrω^EP3037 leads to a slight enhancement of the eye phenotype in Scer\GAL4^GMR.PF,th^{dsRNA.Scer\UAS.cLa} flies. Co-expression of Hsrω^EP93D suppresses, while co-expression of Hsrω^EP3037 has no effect on the pupal lethality of Scer\GAL4^GMR.PF,th^{dsRNA.Scer\UAS.cLa} flies.

Expression of th^{dsRNA.Scer\UAS.cLa} using Scer\GAL4^GMR.PF enhances the rpr^GMR.PW and grim^GMR.PH small eye phenotypes.

Co-expression of th^{dsRNA.Scer\UAS.cLa} enhances the eye phenotype of Scer\GAL4^GMR.PF, egr^Scer\UAS.cIa flies.

(Mallik and Lakhotia, 2009)

Co-expression of Hsp60D^{dsRNA.Sym.Scer\UAS} has no effect on the eye phenotypes caused by expression of th^{dsRNA.Scer\UAS.cLa} under the control of Scer\GAL4^GMR.PF.

Co-expression of Hsp60D^Scer\UAS.cAa mildly enhances the eye phenotypes caused by expression of th^{dsRNA.Scer\UAS.cLa} under the control of Scer\GAL4^GMR.PF.

(Arya and Lakhotia, 2008)

The small eye phenotype observed in animals expressing th^{dsRNA.Scer\UAS.cLb} under the control of Scer\GAL4^GMR.PF is suppressed by co-expression of Iap2^Scer\UAS.cRa, Iap2^{C46G.Scer\UAS}, or Iap2^{C149G.Scer\UAS}. Co-expression of Iap2^{C249G.Scer\UAS} or Iap2^{C466Y.Scer\UAS} fails to suppress this phenotype.

(Ribeiro et al., 2007)

The death of eye pigment cells observed in animals expressing th^{dsRNA.Scer\UAS.cLb} under the control of Scer\GAL4^GMR.PF is enhanced in a Df(3L)H99/Df(3L)H99 mutant background.

(Leulier et al., 2006)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Diap1^RNAi.UAS.cLa is rescued by Scer\GAL4^GMR.PF/Diap1^UAS.cHa

(Leulier et al., 2006)

Comments

The eye phenotype in animals expressing th^{dsRNA.Scer\UAS.cLb} under the control of Scer\GAL4^GMR.PF is fully rescued by co-expression of th^Scer\UAS.cHa.

(Leulier et al., 2006)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (6)

Reported As

Symbol Synonym

Diap1^RNAi.UAS.cLa

Diap1^{dsRNA.Scer\UAS.cLa}

Diap1^{dsRNA.Scer\UAS.cLb}

Diap1^{dsRNA.UAS.cLa}

th^{dsRNA.Scer\UAS.cLa}

th^{dsRNA.Scer\UAS.cLb}

Name Synonyms

Secondary FlyBase IDs

FBal0241524
FBal0244096

References (11)

Report Sections

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General Information
Nature of the Allele
Expression Data
Human Disease Associations
Phenotypic Data
Interactions
Complementation and Rescue Data
Images
Stocks
Notes On Origin
Crossreferences
Synonyms and Secondary IDs
References