FB2025_01 , released February 20, 2025
Allele: Dmel\PtenRNAi.UAS.cUa
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General Information
Symbol
Dmel\PtenRNAi.UAS.cUa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Unknown
FlyBase ID
FBal0317121
Feature type
allele
Associated gene
Dmel\Pten
Associated Insertion(s)
Carried in Construct
P{UAS-Pten.RNAi.U}
Key Links
Transgenic product class
RNAi_reagent
(Levayer et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
RNAi_reagent
(Levayer et al., 2015)
Mutagen
in vitro construct
(Levayer et al., 2015)
Progenitor genotype
Carried in construct
P{UAS-Pten.RNAi.U}
Cytology
Description

UAS regulatory sequences drive expression of sequences targeting Pten.

(Levayer et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Pten
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      There is an increase in the frequency of clone splitting in the PtendsRNA.Scer\UAS.cUa-expressing 'loser' cells when cell competition is induced in the pupal notum through generation of clones expressing PtendsRNA.Scer\UAS.cUa under the control of Scer\GAL4Scer\FRT.Act5C in wild type tissues compared with wild type clones in wild type tissue. The 'loser' clones show reduced compactness over time.

      (Levayer et al., 2015)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      NOT suppressed by
      Other
      Phenotype Manifest In
      Suppressed by
      NOT suppressed by
      Suppressor of
      NOT Suppressor of
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      PtenRNAi.UAS.cUa
      PtendsRNA.Scer\UAS.cUa
      PtendsRNA.UAS.cUa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Unknown
      Secondary FlyBase IDs
        References (5)