FB2025_01 , released February 20, 2025
Allele: Hsap\ELAVL1elav.Tag:HA
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General Information
Symbol
Hsap\ELAVL1elav.Tag:HA
Species
H. sapiens
Name
FlyBase ID
FBal0318112
Feature type
allele
Associated gene
Hsap\ELAVL1
Associated Insertion(s)
Carried in Construct
M{elav-ELAVL1.HA}
Key Links
Transgenic product class
wild_type
(Zaharieva et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Zaharieva et al., 2015)
Mutagen
in vitro construct
(Zaharieva et al., 2015)
Progenitor genotype
Carried in construct
M{elav-ELAVL1.HA}
Cytology
Description

The elav open reading frame in elavTag:HA has been replaced with the open reading frame for Hsap\ELAVL1.

(Zaharieva et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
elav
Encoded product / tool
Hsap\ELAVL1
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Hsap\ELAVL1elav.Tag:HA is a suppressor of abnormal neuroanatomy | third instar larval stage | conditional phenotype of elav5/elavts1

      (Zaharieva et al., 2015)

      Hsap\ELAVL1elav.Tag:HA is a suppressor of lethal phenotype of elav5

      (Zaharieva et al., 2015)

      Hsap\ELAVL1elav.Tag:HA is a suppressor of lethal phenotype of elavts1

      (Zaharieva et al., 2015)
      Phenotype Manifest In
      Suppressor of
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Hsap\ELAVL1elav.T:Ivir\HA1 partially rescues the viability of elavts1.

      Expression of Hsap\ELAVL1elav.T:Ivir\HA1 slightly rescues the viability of elav5.

      Expression of Hsap\ELAVL1elav.T:Ivir\HA1 rescues the reduction in bouton number seen in elavts1/elav5 mutant larvae (raised at the permissive temperature during embryonic development).

      (Zaharieva et al., 2015)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Hsap\ELAVL1elav.T:Ivir\HA1
      Hsap\ELAVL1elav.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)