FB2025_01 , released February 20, 2025
Allele: Dmel\Urm1UAS.cKa
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General Information
Symbol
Dmel\Urm1UAS.cKa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Khoshnood
FlyBase ID
FBal0319059
Feature type
allele
Associated gene
Dmel\Urm1
Associated Insertion(s)
Carried in Construct
P{UAS-Urm1.WT}
Key Links
Transgenic product class
cDNA
(Khoshnood et al., 2016)
wild_type
(Khoshnood et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Khoshnood et al., 2016)
wild_type
(Khoshnood et al., 2016)
Mutagen
in vitro construct
(Khoshnood et al., 2016)
Progenitor genotype
Carried in construct
P{UAS-Urm1.WT}
Cytology
Description

UASt regulatory sequences drive expression of the Urm1 IP20063 cDNA.

(Khoshnood et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Urm1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Urm1Scer\UAS.cKa in the developing wing disc by Scer\GAL4Bx-MS1096 leads to around 50% loss of the anterior crossvein. Flies with expression of Urm1Scer\UAS.cKa driven by Scer\GAL4Act5C.PU do not show significant differences to controls under exposure to oxidative stress (10mM paraquat).

      (Khoshnood et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhanced by
      Enhancer of
      Phenotype Manifest In
      Enhanced by
      Enhancer of
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of Uba4Scer\UAS.cKa and Urm1Scer\UAS.cKa driven in the developing wing disc by Scer\GAL4Bx-MS1096 leads to increased loss (around 65%) of the anterior crossvein compared to expression of Uba4Scer\UAS.cKa or Urm1Scer\UAS.cKa alone.

      (Khoshnood et al., 2016)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4Act5C.PU/Urm1UAS.cKa rescues Urm1n123

      (Khoshnood et al., 2016)
      Comments

      Expression of Urm1Scer\UAS.cKa driven ubiquitously by Scer\GAL4Act5C.PU rescues lethality in Urm1n123/Urm1n123 animals.

      (Khoshnood et al., 2016)
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Urm1Scer\UAS.cKa
      Urm1UAS.cKa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Khoshnood
      Secondary FlyBase IDs
        References (1)