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General Information
Symbol
Dmel\ZnT86DUAS.cDa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Dechen
FlyBase ID
FBal0319545
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of the full-length ZnT86D open reading frame.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Ectopic expression of ZnT86DScer\UAS.cDa under the control of Scer\GAL4GMR.long results in flatter adult eyes of normal size and patchy loss of pigmentation, when two copies of the ZnT86DScer\UAS.cDa are used, the eye size is significantly reduced but no de-pigmentation is observed.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
Suppressed by
Statement
Reference
NOT suppressed by
Statement
Reference
Other
Phenotype Manifest In
Enhanced by
Statement
Reference
Suppressed by
NOT suppressed by
Statement
Reference
Additional Comments
Genetic Interactions
Statement
Reference

The morphological defects in the adult eye seen upon expression of ZnT86DScer\UAS.cDa under the control of Scer\GAL4GMR.long are exacerbated to a varying degree by co-expression of any of the following: Zip42C.1Scer\UAS.T:Zzzz\FLAG, Zip42C.2Scer\UAS.T:Zzzz\FLAG, ZnT86DScer\UAS.cDa, Zip71BScer\UAS.T:Zzzz\FLAG, Zip88EScer\UAS.T:Zzzz\FLAG, Zip89BScer\UAS.T:Zzzz\FLAG, Zip99CScer\UAS.T:Zzzz\FLAG, Zip102BScer\UAS.T:Zzzz\FLAG, foiScer\UAS.T:Zzzz\FLAG, CatsupScer\UAS.cLa.T:Zzzz\FLAG, CatsupKK103630, ZnT35CScer\UAS.T:Zzzz\FLAG, ZnT41FScer\UAS.T:Zzzz\FLAG, ZnT49BGD1962, ZnT63CScer\UAS.T:Zzzz\FLAG, ZnT77CScer\UAS.T:Zzzz\FLAG.

The pigmentation defects in the adult eye seen upon expression of ZnT86DScer\UAS.cDa under the control of Scer\GAL4GMR.long are exacerbated to a varying degree by co-expression of any of the following: Zip42C.1Scer\UAS.T:Zzzz\FLAG, Zip42C.2Scer\UAS.T:Zzzz\FLAG, Zip42C.2GD1831, Zip71BScer\UAS.T:Zzzz\FLAG, Zip89BScer\UAS.T:Zzzz\FLAG, foiScer\UAS.T:Zzzz\FLAG, foiGD2367, CatsupKK103630, ZnT33DKK100432, ZnT41FGD4522, ZnT49BGD1962, ZnT63CKK102261.

The morphological defects in the adult eye seen upon expression of ZnT86DScer\UAS.cDa under the control of Scer\GAL4GMR.long are ameliorated to a varying degree by co-expression of any of the following: Zip88EKK110168.

The pigmentation defects in the adult eye seen upon expression of ZnT86DScer\UAS.cDa under the control of Scer\GAL4GMR.long are ameliorated to a varying degree by co-expression of any of the following: Zip48CKK101374, Zip88EScer\UAS.T:Zzzz\FLAG, Zip88EKK110168, Zip99CScer\UAS.T:Zzzz\FLAG, Zip102BScer\UAS.T:Zzzz\FLAG, CatsupScer\UAS.cLa.T:Zzzz\FLAG, ZnT41FScer\UAS.T:Zzzz\FLAG, ZnT63CScer\UAS.T:Zzzz\FLAG, ZnT77CScer\UAS.T:Zzzz\FLAG.

The morphological and pigmentation defects in the adult eye seen upon expression of ZnT86DScer\UAS.cDa under the control of Scer\GAL4GMR.long are not changed by co-expression of any of the following: Zip71BGD2461, Zip89BGD3013, Zip99CGD370, Zip102BGD3683, ZnT33DScer\UAS.PB.T:Zzzz\FLAG, ZnT35CKK112697, ZnT77CGD2749.

The morphological defects in the adult eye seen upon expression of ZnT86DScer\UAS.cDa under the control of Scer\GAL4GMR.long are not changed (unlike the loss of pigmentation phenotype, which is modified) by co-expression of any of the following: Zip42C.2GD1831, Zip48CKK101374, foiGD2367, ZnT33DKK100432, ZnT41FGD4522, ZnT63CKK102261.

The loss of pigmentation defect in the adult eye seen upon expression of ZnT86DScer\UAS.cDa under the control of Scer\GAL4GMR.long is not changed (unlike the morphological phenotype, which is modified) by co-expression of any of the following: Zip48CScer\UAS.T:Zzzz\FLAG, ZnT35CScer\UAS.T:Zzzz\FLAG.

Co-expression of any of the following: Zip71BScer\UAS.T:Zzzz\FLAG, Zip89BScer\UAS.T:Zzzz\FLAG, foiScer\UAS.T:Zzzz\FLAG, CatsupKK103630

together with ZnT86DScer\UAS.cDa under the control of Scer\GAL4GMR.long leads to partial lethality even at 18[o]C.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

The eye phenotype (flat shape, partial loss of pigmentation) observed upon expression of ZnT86DScer\UAS.cDa under the control of the Scer\GAL4GMR.long driver can be fully restored by co-expression of ZnT86DKK101698 RNAi.

The adult eye phenotype seen upon expression of ZnT86DScer\UAS.cDa under the control of Scer\GAL4GMR.long can be modified by co-expression of ZnT86DScer\UAS.T:Zzzz\FLAG : the morphological defects are mildly worsened whereas the pigmentation loss is unchanged.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
ZnT86DScer\UAS.cDa
ZnT86DUAS.cDa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Dechen
Secondary FlyBase IDs
    References (1)