FB2020_06, released Dec 22, 2020

Allele: Dmel\SCCRO4VDRC.cUa

Open Close
General Information
Symbol
Dmel\SCCRO4VDRC.cUa
Species
D. melanogaster
Name
FlyBase ID
FBal0320344
Feature type
allele
Associated gene
Dmel\SCCRO4
Associated Insertion(s)
Carried in Construct
P{VDRC.SCCRO4.U}
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - regulatory fusion
(Fu et al., 2016)
in vitro construct - RNAi
(Fu et al., 2016)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Carried in construct
      P{VDRC.SCCRO4.U}
      Cytology
      Nature of the lesion
      Statement
      Reference

      UAS regulatory sequences drive expression of an RNAi line that targets SCCRO4.

      (Fu et al., 2016)
      Allele components
      Product class / Tool use(s)
      Regulatory region(s)
      UAS
      Encoded product / tool
      SCCRO4
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of an RNAi line against SCCRO4 (unspecified, either SCCRO4GD12417 or SCCRO4KK108635) driven ubiquitously by Scer\GAL4Act5C.PI or Scer\GAL4Ubi.PU causes late pupal lethality; expression in the eye (by 'Ey-GMR-GAL4', unclear if this is Scer\GAL4ey.PH or Scer\GAL4GMR.PF) results in larger, rough eyes compared to controls; when expression is driven by Scer\GAL4ptc.PU, there is a significant increase in the L3-L4 distance (due to a significant increase in cell number, but no change in cell size) in the wing and macrochaetae on the notum are larger.

      (Fu et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      SCCRO4VDRC.cUa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)