FB2025_02 , released April 17, 2025
Allele: Dmel\Cdk1Y15F.βTub85D.GFP
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General Information
Symbol
Dmel\Cdk1Y15F.βTub85D.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0321371
Feature type
allele
Associated gene
Dmel\Cdk1
Associated Insertion(s)
Carried in Construct
P{βTub85D-Cdk1.Y15F.GFP}
Key Links
Transgenic product class
missense_variant
(Varadarajan et al., 2016)
polypeptide_post_translational_processing_variant
(Varadarajan et al., 2016)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Varadarajan et al., 2016)
polypeptide_post_translational_processing_variant
(Varadarajan et al., 2016)
Mutagen
in vitro construct
(Varadarajan et al., 2016)
Progenitor genotype
Carried in construct
P{βTub85D-Cdk1.Y15F.GFP}
Cytology
Description

βTub85D promoter sequences drive expression of Cdk1 that has been mutated so it cannot be phosphorylated on residue Y15. The protein is tagged with GFP.

(Varadarajan et al., 2016)
Allele components
Component
Use(s)
Regulatory region(s)
βTub85D
Encoded product / tool
Cdk1
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Cdk1Y15F.βTub85D.T:Avic\GFP expression results in obvious fusome defects in stage S5-S6 spermatocytes.

      (Varadarajan et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Cdk1Y15F.βTub85D.GFP
      Cdk1Y15F.βTub85D.T:Avic\GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)