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General Information
Symbol
Dmel\lncRNA:CR43862KO
Species
D. melanogaster
Name
FlyBase ID
FBal0322662
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
deletion
Comment:

lncRNA region removed by targeted deletion.

Reported_genomic_loc:

X_r6:20686819..20687653

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

The entire lncRNA gene has been knocked out and replaced with an attP site followed by an FRT-flanked Disc\RFP3xP3.cUa fluorescent marker.

Insertion components
TI{TI}lncRNA:CR43862KO
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

CR43862KO homozygote males show reduced fertility compared to wild-type controls and display defects in spermatid morphogenesis (mutant testes contain sperm cells that are scattered or curled).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

The late spermatogenesis defects observed in CR43862KO homozygous males are rescued by lncRNA restoration with CR43862+tWa both in cis (in situ rescue) and in trans.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
CR43862KO
lncRNA:CR43862KO
Name Synonyms
Secondary FlyBase IDs
    References (1)