FlyBase Allele Report: Zzzz\GGGGCC[58.UAS.EGFP]

General Information

Symbol

Zzzz\GGGGCC^58.UAS.EGFP

Species

a. artificial

Name

FlyBase ID

FBal0323570

Feature type

allele

Associated gene

Zzzz\GGGGCC

Associated Insertion(s)

Carried in Construct

P{UAS-GGGGCC.58}

Allele class

Mutagen

in vitro construct - regulatory fusion

Nature of the Allele

Allele class

Mutagen

in vitro construct - regulatory fusion

(Freibaum et al., 2015)

Mutations Mapped to the Genome

Type

Location

Additional Notes

References

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Progenitor genotype

Carried in construct

P{UAS-GGGGCC.58}

Cytology

Nature of the lesion

Statement

Reference

UASt regulatory sequences drive expression of 58 copies of a G[[4]C[[2]] repeat followed by the EGFP coding sequence without a start codon.

(Freibaum et al., 2015)

Allele components

Product class / Tool use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Zzzz\GGGGCC

Tagged with

EGFP

green fluorescent protein

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of amyotrophic lateral sclerosis

CEA

(Freibaum et al., 2015)

model of frontotemporal dementia

CEA

(Freibaum et al., 2015)

model of frontotemporal dementia and/or amyotrophic lateral sclerosis-1

CEC

(Cheng et al., 2019)

CEA

(Ramesh et al., 2020)

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

model of amyotrophic lateral sclerosis

is exacerbated by Nup50^GD9739

(Freibaum et al., 2015)

is exacerbated by Nup50^KG09557

(Freibaum et al., 2015)

is exacerbated by Nup50^KK108150

(Freibaum et al., 2015)

is exacerbated by Ran^{T24N.UASp.Tag:HA}

(Freibaum et al., 2015)

is exacerbated by CG9775^KK110941

(Freibaum et al., 2015)

is exacerbated by Nup153^GD10636

(Freibaum et al., 2015)

is exacerbated by Cbp20^KK109448

(Freibaum et al., 2015)

is exacerbated by Nup153^KK110135

(Freibaum et al., 2015)

is exacerbated by Cbp80^KK100796

(Freibaum et al., 2015)

is exacerbated by Cbp80^GD12110

(Freibaum et al., 2015)

is exacerbated by Ars2^KK109705

(Freibaum et al., 2015)

is exacerbated by Tnpo^KK108990

(Freibaum et al., 2015)

is ameliorated by Ref1⁰²²⁶⁷

(Freibaum et al., 2015)

is exacerbated by Gle1^JF01431

(Freibaum et al., 2015)

is exacerbated by Ars2^HMS00626

(Freibaum et al., 2015)

is exacerbated by sbr^GD14541

(Freibaum et al., 2015)

is exacerbated by Ars2^GL00079

(Freibaum et al., 2015)

is exacerbated by sbr^KK100882

(Freibaum et al., 2015)

is exacerbated by Rrp6^KK100590

(Freibaum et al., 2015)

is exacerbated by sbr^HM05135

(Freibaum et al., 2015)

is exacerbated by Rrp40^GD10414

(Freibaum et al., 2015)

is ameliorated by Nup98-96^KK100388

(Freibaum et al., 2015)

is ameliorated by Nup98-96^GD6897

(Freibaum et al., 2015)

is ameliorated by Nup107^KK108047

(Freibaum et al., 2015)

is ameliorated by Nup107^GD12024

(Freibaum et al., 2015)

is ameliorated by Nup160^KK104805

(Freibaum et al., 2015)

is exacerbated by emb^JF01311

(Freibaum et al., 2015)

is exacerbated by LBR^HMC02426

(Freibaum et al., 2015)

model of frontotemporal dementia

is exacerbated by Nup50^GD9739

(Freibaum et al., 2015)

is exacerbated by Nup50^KG09557

(Freibaum et al., 2015)

is exacerbated by Nup50^KK108150

(Freibaum et al., 2015)

is exacerbated by Ran^{T24N.UASp.Tag:HA}

(Freibaum et al., 2015)

is exacerbated by LBR^HMC02426

(Freibaum et al., 2015)

is exacerbated by Nup153^GD10636

(Freibaum et al., 2015)

is exacerbated by CG9775^KK110941

(Freibaum et al., 2015)

is exacerbated by Cbp20^KK109448

(Freibaum et al., 2015)

is exacerbated by Cbp80^KK100796

(Freibaum et al., 2015)

is exacerbated by Cbp80^GD12110

(Freibaum et al., 2015)

is exacerbated by Nup153^KK110135

(Freibaum et al., 2015)

is exacerbated by Tnpo^KK108990

(Freibaum et al., 2015)

is ameliorated by Ref1⁰²²⁶⁷

(Freibaum et al., 2015)

is exacerbated by Ars2^KK109705

(Freibaum et al., 2015)

is exacerbated by Ars2^HMS00626

(Freibaum et al., 2015)

is exacerbated by Gle1^JF01431

(Freibaum et al., 2015)

is exacerbated by sbr^GD14541

(Freibaum et al., 2015)

is exacerbated by Ars2^GL00079

(Freibaum et al., 2015)

is exacerbated by Rrp6^KK100590

(Freibaum et al., 2015)

is exacerbated by sbr^KK100882

(Freibaum et al., 2015)

is exacerbated by sbr^HM05135

(Freibaum et al., 2015)

is exacerbated by Rrp40^GD10414

(Freibaum et al., 2015)

is ameliorated by Nup98-96^KK100388

(Freibaum et al., 2015)

is ameliorated by Nup98-96^GD6897

(Freibaum et al., 2015)

is ameliorated by Nup107^KK108047

(Freibaum et al., 2015)

is ameliorated by Nup107^GD12024

(Freibaum et al., 2015)

is ameliorated by Nup160^KK104805

(Freibaum et al., 2015)

is exacerbated by emb^JF01311

(Freibaum et al., 2015)

model of frontotemporal dementia and/or amyotrophic lateral sclerosis-1

is exacerbated by bel^EY08943

(Cheng et al., 2019)

is exacerbated by bel^GL00205

(Cheng et al., 2019)

is exacerbated by bel^JF02884

(Cheng et al., 2019)

is ameliorated by Hsap\MATR3^UAS.Tag:FLAG

(Ramesh et al., 2020)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal eye color | adult stage, with Scer\GAL4^GMR.PF

(Ramesh et al., 2020)

abnormal locomotor behavior | larval stage, with Scer\GAL4^elav.PU

(Freibaum et al., 2015)

abnormal locomotor behavior | larval stage, with Scer\GAL4^VGlut-OK371

(Freibaum et al., 2015)

abnormal neuroanatomy | larval stage, with Scer\GAL4^VGlut-OK371

(Freibaum et al., 2015)

abnormal size | larval stage, with Scer\GAL4^elav.PU

(Freibaum et al., 2015)

abnormal size | larval stage, with Scer\GAL4^VGlut-OK371

(Freibaum et al., 2015)

visible, with Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

visible | adult stage, with Scer\GAL4^GMR.PF

(Ramesh et al., 2020)

visible | progressive, with Scer\GAL4^Mhc.PU

(Freibaum et al., 2015)

Phenotype Manifest In

embryonic/larval neuromuscular junction | larval stage, with Scer\GAL4^VGlut-OK371

(Freibaum et al., 2015)

embryonic/larval salivary gland | third instar larval stage, with Scer\GAL4^fkh.PH

(Freibaum et al., 2015)

eye, with Scer\GAL4^GMR.PF

(Ramesh et al., 2020)

eye, with Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

indirect flight muscle cell | progressive, with Scer\GAL4^Mhc.PU

(Freibaum et al., 2015)

interommatidial bristle, with Scer\GAL4^GMR.PF

(Ramesh et al., 2020)

NMJ bouton | larval stage, with Scer\GAL4^VGlut-OK371

(Freibaum et al., 2015)

nuclear envelope | third instar larval stage, with Scer\GAL4^fkh.PH

(Freibaum et al., 2015)

ommatidium, with Scer\GAL4^GMR.PF

(Ramesh et al., 2020)

presynaptic active zone | larval stage, with Scer\GAL4^VGlut-OK371

(Freibaum et al., 2015)

wing | progressive, with Scer\GAL4^Mhc.PU

(Freibaum et al., 2015)

Detailed Description

Statement

Reference

The expression of Zzzz\GGGGCC^58.UAS.EGFP under the control of Scer\GAL4^GMR.PF external eye degeneration including ommatidial fusion, bristle disorganization and depigmentation.

(Ramesh et al., 2020)

Expression of Zzzz\GGGGCC^{58.Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PU results in a rough eye phenotype.

Expression of Zzzz\GGGGCC^{58.Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^fkh.PH leads to a subset of third instar salivary gland cells exhibiting a wrinkled and defective nuclear envelope.

Expression of two copies of Zzzz\GGGGCC^{58.Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^VGlut-OK371 leads to small larvae with significantly impaired locomotor activity, and neuromuscular junctions in these larvae exhibit a significant decrease in bouton number, active zones, and total muscle area, as compared to controls.

Expression of 2 copies, but not 1 copy of Zzzz\GGGGCC^{58.Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^elav.PU leads to a significant decrease in larval size and locomotor activity, as compared to controls.

Expression of Zzzz\GGGGCC^{58.Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^Mhc.PU leads to age-dependent defects in indirect flight muscle, resulting in permanent abnormal wing position as compared to controls.

(Freibaum et al., 2015)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by +/Df(3L)1-16

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by sbr^HM05135/Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Cbp80^GD12110, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Ars2^HMS00626, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Ars2^GL00079, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(3L)BSC775/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(3L)ED4470/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(3L)Exel6109/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by +/Df(3R)A113

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(3R)BSC141/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(3R)BSC476/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(3R)BSC677/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(3R)BSC681/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(3R)BSC748/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(3R)ED50003/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(3L)BSC119/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(3R)ED5577/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(2L)ED108/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(2L)ED279/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by +/Df(2L)ED369

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(2L)ED623/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(2L)ED700/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by +/Df(2L)ED773

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by +/Df(2L)ED778

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(2L)ED779/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(2L)ED929/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(3L)BSC181/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(2L)ED7853/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(2R)ED1725/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(2R)ED1735/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(2R)ED2222/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by +/Df(2R)ED2747

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(2R)ED3791/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by +/Df(2R)ED3923

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Nup50^GD9739, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Nup50^KG09557

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Ran^{T24N.UASp.Tag:HA}

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(3L)BSC20/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Nup50^KK108150, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Nup153^GD10636, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Nup153^KK110135, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Tnpo^KK108990/Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Gle1^JF01431, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by sbr^GD14541/Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by LBR^HMC02426, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by CG9775^KK110941, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Cbp20^KK109448, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Cbp80^KK100796, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Df(3L)BSC289/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Ars2^KK109705, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Rrp6^KK100590, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by emb^JF01311/Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by Rrp40^GD10414, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, enhanceable by sbr^KK100882/Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, Zzzz\GGGGCC^58.UAS.EGFP has visible | adult stage phenotype, suppressible | partially by Hsap\MATR3^UAS.Tag:FLAG, Scer\GAL4^GMR.PF

(Ramesh et al., 2020)

Scer\GAL4^GMR.PF, Zzzz\GGGGCC^58.UAS.EGFP has abnormal eye color | adult stage phenotype, suppressible | partially by Hsap\MATR3^UAS.Tag:FLAG, Scer\GAL4^GMR.PF

(Ramesh et al., 2020)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Df(3L)AC1/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Df(3L)BSC392/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Df(3L)BSC672/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Df(3L)Exel6092/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Df(3L)Exel6112/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Df(3R)Antp17/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by +/Df(3R)BSC47

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Df(3R)BSC504/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Df(3R)BSC507/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Df(3R)BSC738/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Df(3R)ED2/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by +/Df(3L)BSC113

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Df(3R)ED5495/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Df(3R)ED6232/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by +/Df(3R)L127

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Df(3R)X3F/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Ref1[+]/Ref1⁰²²⁶⁷

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Nup98-96^KK100388, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Nup107^KK108047, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Nup107^GD12024, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Nup160^KK104805, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Nup98-96^GD6897, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Df(3L)BSC220/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Df(3L)BSC23/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has visible phenotype, suppressible by Df(3L)BSC388/+

(Freibaum et al., 2015)

Other

Statement

Reference

Df(3R)BSC567/+, Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has lethal - all die during P-stage phenotype

(Freibaum et al., 2015)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by +/Df(3L)1-16

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(3L)BSC775/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by sbr^HM05135/Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Cbp80^GD12110, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Ars2^HMS00626, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Ars2^GL00079, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(3L)ED4470/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(3L)Exel6109/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by +/Df(3R)A113

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(3R)BSC141/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(3L)BSC119/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(3R)BSC476/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(3R)BSC677/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(3R)BSC681/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(3R)BSC748/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(3R)ED50003/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(3R)ED5577/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(2L)ED108/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(2L)ED279/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by +/Df(2L)ED369

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(2L)ED623/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(3L)BSC181/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(2L)ED700/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by +/Df(2L)ED773

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by +/Df(2L)ED778

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(2L)ED779/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(2L)ED929/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(2L)ED7853/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(2R)ED1725/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(2R)ED1735/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(2R)ED2222/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by +/Df(2R)ED2747

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(3L)BSC20/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(2R)ED3791/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by +/Df(2R)ED3923

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Nup50^GD9739, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Nup50^KG09557

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Ran^{T24N.UASp.Tag:HA}

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Nup50^KK108150, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Nup153^GD10636, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Nup153^KK110135, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Tnpo^KK108990/Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Gle1^JF01431, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Df(3L)BSC289/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by sbr^GD14541/Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by LBR^HMC02426, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by CG9775^KK110941, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Cbp20^KK109448, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Cbp80^KK100796, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Ars2^KK109705, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Rrp6^KK100590, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by emb^JF01311/Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by Rrp40^GD10414, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, enhanceable by sbr^KK100882/Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Suppressed by

Statement

Reference

Scer\GAL4^GMR.PF, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible | partially by Hsap\MATR3^UAS.Tag:FLAG, Scer\GAL4^GMR.PF

(Ramesh et al., 2020)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Df(3L)AC1/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Df(3L)BSC392/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Df(3L)BSC672/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Df(3L)Exel6092/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Df(3L)Exel6112/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Df(3R)Antp17/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by +/Df(3L)BSC113

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by +/Df(3R)BSC47

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Df(3R)BSC504/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Df(3R)BSC507/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Df(3R)BSC738/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Df(3R)ED2/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Df(3R)ED5495/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Df(3R)ED6232/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by +/Df(3R)L127

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Df(3R)X3F/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Ref1[+]/Ref1⁰²²⁶⁷

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Df(3L)BSC220/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Nup98-96^KK100388, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Nup107^KK108047, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Nup107^GD12024, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Nup160^KK104805, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Nup98-96^GD6897, Scer\GAL4^GMR.PU

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Df(3L)BSC23/+

(Freibaum et al., 2015)

Scer\GAL4^GMR.PU, Zzzz\GGGGCC^58.UAS.EGFP has eye phenotype, suppressible by Df(3L)BSC388/+

(Freibaum et al., 2015)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Each of the following mutations enhances the rough eye phenotype observed in flies expressing Zzzz\GGGGCC^{58.Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PU : Df(3L)1-16/+, Df(3L)BSC119/+, Df(3L)BSC181/+, Df(3L)BSC20/+, Df(3L)BSC289/+, Df(3L)BSC775/+, Df(3L)ED4470/+, Df(3L)Exel6109/+, Df(3R)A113/+, Df(3R)BSC141/+, Df(3R)BSC476/+, Df(3R)BSC677/+, Df(3R)BSC681/+, Df(3R)BSC748/+, Df(3R)ED50003/+, Df(3R)ED5577/+, Df(2L)ED108/+, Df(2L)ED279/+, Df(2L)ED369/+, Df(2L)ED623/+, Df(2L)ED700/+, Df(2L)ED773/+, Df(2L)ED778/+, Df(2L)ED779/+, Df(2L)ED929/+, Df(2L)ED7853/+, Df(2R)ED1725/+, Df(2R)ED1735/+, Df(2R)ED2222/+, Df(2R)ED2747/+, Df(2R)ED3791/+, or Df(2R)ED3923/+.

Each of the following mutations suppresses the rough eye phenotype observed in flies expressing Zzzz\GGGGCC^{58.Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PU : Df(3L)AC1/+, Df(3L)BSC113/+, Df(3L)BSC220/+, Df(3L)BSC23/+, Df(3L)BSC388/+, Df(3L)BSC392/+, Df(3L)BSC672/+, Df(3L)Exel6092/+, Df(3L)Exel6112/+, Df(3R)Antp17/+, Df(3R)BSC47/+, Df(3R)BSC504/+, Df(3R)BSC507/+, Df(3R)BSC738/+, Df(3R)ED2/+, Df(3R)ED5495/+, Df(3R)ED6232/+, Df(3R)L127/+, or Df(3R)X3F/+, Ref1⁰²²⁶⁷/+.

Expression of Zzzz\GGGGCC^{58.Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PU in a Df(3R)BSC567/+ background leads to pupal lethality.

Co-expression of Nup50^GD9739, Nup50^KK108150, Nup153^GD10636, Nup153^KK110135, Trn^KK108990, CG14749^JF01431, sbr^GD14541, LBR^HMC02426, CG9775^KK110941, Cbp20^KK109448, Cbp80^KK100796, Ars2^KK109705, Rrp6^KK100590, Rrp40^GD10414, emb^JF01311, sbr^KK100882, sbr^HM05135, Cbp80^GD12110, Ars2^HMS00626, Ars2^GL00079 or presence of the Nup50^KG09557 or Ran^{T24N.Scer\UAS.P\T.T:Ivir\HA1} mutation enhances the rough eye phenotype seen in flies expressing Zzzz\GGGGCC^{58.Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PU.

Co-expression of Nup98-96^KK100388, Nup107^KK108047, Nup107^GD12024, Nup98-96^GD6897 or Nup160^KK104805 suppresses the rough eye phenotype seen in flies expressing Zzzz\GGGGCC^{58.Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PU.

(Freibaum et al., 2015)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Zzzz\GGGGCC^{58.Scer\UAS.T:Avic\GFP-EGFP}

Zzzz\GGGGCC^58.UAS.EGFP

Name Synonyms

Secondary FlyBase IDs

References (4)

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