FB2025_01 , released February 20, 2025
Allele: Dmel\MitfSI1-RES
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General Information
Symbol
Dmel\MitfSI1-RES
Species
D. melanogaster
Name
FlyBase ID
FBal0324143
Feature type
allele
Associated gene
Dmel\Mitf
Associated Insertion(s)
Carried in Construct
P{Mitf.SI1-RES}
Key Links
Transgenic product class
genomic_DNA
(Zhang et al., 2015)
wild_type
(Zhang et al., 2015)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Zhang et al., 2015)
wild_type
(Zhang et al., 2015)
Mutagen
in vitro construct
(Zhang et al., 2015)
Progenitor genotype
Carried in construct
P{Mitf.SI1-RES}
Cytology
Description

Genomic fragment containing Mitf. A 500bp fragment targeted by P{KK113614} has been altered with silent nucleotide changes to produce an RNAi resistant rescue construct.

(Zhang et al., 2015)
Allele components
Component
Use(s)
Regulatory region(s)
Mitf
Encoded product / tool
Mitf
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4byn-Gal4/MitfSI1-RES rescues MitfKK113614

      (Zhang et al., 2015)
      Partially rescues

      Scer\GAL4Act5C.PI/MitfSI1-RES partially rescues MitfKK113614

      (Zhang et al., 2024)
      Comments

      The early larval lethality of animals expressing MitfKK113614 under the control of Scer\GAL4byn-Gal4 is rescued by co-expression of MitfSI1-RES.

      (Zhang et al., 2015)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      MitfSI-RES
      (Cunningham et al., 2020)
      MitfSI1-RES
      Name Synonyms
      Secondary FlyBase IDs
        References (3)