FB2025_01 , released February 20, 2025
Allele: Scer\GAL4Pde4.RA
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General Information
Symbol
Scer\GAL4Pde4.RA
Species
S. cerevisiae
Name
FlyBase ID
FBal0325392
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{Pde4-GAL4.RA}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Ruppert et al., 2017)
Progenitor genotype
Carried in construct
P{Pde4-GAL4.RA}
Cytology
Description

The putative promoter region (base pairs -4947 to +1066) of the dnc[RA] isoform regulates expression of a GAL4 driver.

(Ruppert et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
Pde4
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      adult antennal lobe | subset
      (Ruppert et al., 2017)
      calyx of adult mushroom body
      (Ruppert et al., 2017)
      lobe system of adult mushroom body | restricted
      (Ruppert et al., 2017)
      adult gnathal ganglion | restricted | ventral
      (Ruppert et al., 2017)
      adult fan-shaped body layer 1 tangential neuron | subset
      (Ruppert et al., 2017)
      protocerebral bridge glomerulus | subset
      (Ruppert et al., 2017)
      fan-shaped body | subset
      (Ruppert et al., 2017)
      nodulus 3 posterior domain
      (Ruppert et al., 2017)
      ellipsoid body inner posterior domain | faint | restricted
      (Ruppert et al., 2017)
      adult dopaminergic PAM neuron | subset
      (Ruppert et al., 2017)
      adult salivary gland
      (Ruppert et al., 2017)
      Additional Information
      Statement
      Reference

      In the central complex ScerGAL4dnc.RA drives expression in a number of neurons, including some that innervate the glomeruli of the protocerebral bridge, innervate tangentially within the fan-shaped body or that project specifically into the posterior noduli while avoiding the anterior noduli. ScerGAL4dnc.RA also drives expression in the hang-XP positive F1 neurons in the brain as well as a subset of ple-XP positive dopaminergic PAM neurons.

      (Ruppert et al., 2017)
       
      Marker for
      Reflects expression of
      Pde4
      (Ruppert et al., 2017)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Scer\GAL4Pde4.RA
      Scer\GAL4dnc.RA
      Name Synonyms
      Secondary FlyBase IDs
        References (2)