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General Information
Symbol
Dmel\eyaRB.enh1
Species
D. melanogaster
Name
FlyBase ID
FBal0325582
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

A 275bp enhancer 1 minimal fragment corresponding to -1171 to -897 relative to the transcription start site of the eya-RB isoform is fused upstream of a minimal Hsp70 promoter followed by a cDNA encoding the eya-RB isoform (plus 3'UTR).

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Adult eya1 homozygous mutants are eyeless, eya1 homozygous flies carrying the eyaRB.enh1 transgene display small eyes (partial rescue).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference
Suppressor of
Statement
Reference
Phenotype Manifest In
Suppressed by
Statement
Reference

eya1, eyaRB.enh1 has eye | adult stage phenotype, suppressible by eyaRB.enhE

Suppressor of
Statement
Reference

eyaRB.enh1 is a suppressor of eye phenotype of eya1, eyaRB.enhE

Additional Comments
Genetic Interactions
Statement
Reference

The small eye phenotype characteristic for eya1 homozygotes carrying the eyaRB.enhE transgene, i.e. partial rescue of the eyeless phenotype of the eya1 mutants, is improved further by combination with eyaRB.enh1 (which on its own also partially rescues the no-eye phenotype of eya1 mutants).

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Comments

Expression of eyaRB.enh1 partially rescues the no-eye phenotype observed either eya2 or eya1 homozygote adults, the rescue effect is stronger in the eya2 mutants.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
eyaRB.enh1
Name Synonyms
Secondary FlyBase IDs
    References (1)