axedCrisprB contains a 14 bp deletion in the axed coding region as well as many missense mutations ( chr3L:6616215..6616481 ).
14bp deletion in exon 2 of axed.
wound healing defective | adult stage | somatic clone
axon | adult stage | somatic clone
Flies carrying axedCrisprB mutant somatic clones show defective injury-induced axon degeneration: severed axons in sensory neurons in the adult wing remain intact for a full week after an axotomy, instead of being cleared away.
axedCrisprB fails to complement the lethality of either axed0011 or axed2094 mutants.