FB2020_06, released Dec 22, 2020

Allele: Dmel\axedMI13270-GFSTF.1

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General Information
Symbol
Dmel\axedMI13270-GFSTF.1
Species
D. melanogaster
Name
FlyBase ID
FBal0327541
Feature type
allele
Associated gene
Dmel\axed
Associated Insertion(s)
Mi{PT-GFSTF.1}axedMI13270-GFSTF.1
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
phiC31 integrase
(Neukomm et al., 2017)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Mi{MIC}axedMI13270
      (Neukomm et al., 2017)
      Cytology
      Nature of the lesion
      Statement
      Reference

      The RMCE cassette of the Mi{MIC}axedMI13270 insertion has been replaced with a EGFP-FlAsH-StrepII-TEV-3xFlag multi-tag cassette (phase 1).

      (Neukomm et al., 2017)
      Insertion components
      Mi{PT-GFSTF.1}axedMI13270-GFSTF.1
      Product class / Tool use(s)
      Encoded product / tool
      Tagged with
      EGFP
      Tag:CALI(TC)
      Tag:CS(TEVp)
      Tag:FLAG
      Tag:StrepII
      Expression Data
      Reporter Expression
      distribution deduced from reporter or direct label
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      larval stage
      ventral nerve cord
      (Neukomm et al., 2017)
      adult stage
      neuron of adult brain
      (Neukomm et al., 2017)
      Additional Information
      Statement
      Reference

      tagged axed protein localizes to axons throughout the larval peripheral nerves. In CNS, axed is enriched in synaptic neuropil of the larval ventral nerved cord and the adult brain. It is expressed in neurons and enriched in neuronal processes.

      (Neukomm et al., 2017)
       
      Marker for
      Reflects expression of
      axed
      (Neukomm et al., 2017)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      axedMI13270-GFSTF.1
      axedeGFP::FLAG
      (Neukomm et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)