FB2025_01 , released February 20, 2025
Allele: Dmel\SNF4AγMI09417-TG4.1
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General Information
Symbol
Dmel\SNF4AγMI09417-TG4.1
Species
D. melanogaster
Name
FlyBase ID
FBal0327669
Feature type
allele
Associated gene
Dmel\SNF4Aγ
Associated Insertion(s)
Mi{Trojan-GAL4.1}SNF4AγMI09417-TG4.1
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Nagarkar-Jaiswal et al., 2017)
Mutagen
phiC31 integrase
(Gene Disruption Project members, 2016-)
Progenitor genotype
Mi{MIC}SNF4AγMI09417
(Gene Disruption Project members, 2016-)
Associated Insertion(s)
Mi{Trojan-GAL4.1}SNF4AγMI09417-TG4.1
Cytology
Description

The RMCE cassette of the Mi{MIC}SNF4AγMI09417 insertion has been replaced with a Trojan-Gal4 cassette. The insertion is in a coding intron of some of the annotated transcripts of SNF4Aγ (predicted to gene trap the gene) and in an intron of the 5' UTR of some of the other annotated transcripts of SNF4Aγ.

(Gene Disruption Project members, 2016-)
Allele components
Component
Use(s)
Inserted element
Mi{Trojan-GAL4.1}
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Scer\FLP1Scer\UAS.cUa;SNF4AγMI09417-FF.PT-EGFP/SNF4AγMI09417-TG4.1 flies (using the Scer\GAL4SNF4Aγ-MI09417-TG4.1 driver inherent in the SNF4AγMI09417-TG4.1 allele to drive the flippase and thus inactivate expression from the SNF4AγMI09417-FF.PT-EGFP allele by inverting the 'flip-flop' insertion it contains) die as poorly developed pupae and are slim and elongated in the larval stage relative to controls.

      (Nagarkar-Jaiswal et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      In lethality complementation tests the SNF4AγMI09417-TG4.1/Df(3R)e-R1 and SNF4AγMI09417-TG4.1/SNF4AγMI09417 flies are lethal but SNF4AγMI09417-TG4.1/SNF4AγMI09417-FF.PT-EGFP are viable.

      (Nagarkar-Jaiswal et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      SNF4AγMI09417-TG4.1
      SNF4AγMI09417T2A>GAL4
      (Nagarkar-Jaiswal et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)