FB2025_01 , released February 20, 2025
Allele: Ecol\lexAppk.PE
Open Close
General Information
Symbol
Ecol\lexAppk.PE
Species
E. coli
Name
FlyBase ID
FBal0336342
Feature type
allele
Associated gene
Ecol\lexA
Associated Insertion(s)
Carried in Construct
P{ppk-lexA.E}
Also Known As
ppk-LexA
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Tsubouchi et al., 2017)
Progenitor genotype
Carried in construct
P{ppk-lexA.E}
Cytology
Description

ppk regulatory sequences drive expression of a lexA::UnkAD driver.

(Tsubouchi et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
ppk
Encoded product / tool
lexA::UnkAD
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      larval stage
      larval multidendritic class IV neuron
      (Luedke et al., 2024)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      ppk
      (Luedke et al., 2024)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Optogenetic activation (using Crei\ChR1::Vcar\ChR1::Vcar\ChR2ReaChR.lexAop.Citrine with 617 nm (red) light) of Ecol\lexAppk.PE cells in larvae results in an induction of nociceptive rolling behavior in the absence of nociceptive stimuli, unlike controls.

      (Yoshino et al., 2017)
      External Data
      Interactions
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ecol\lexAppk.PE
      Name Synonyms
      Secondary FlyBase IDs
        References (5)