FB2025_01 , released February 20, 2025
Allele: Dmel\cnk5xAIR.UAS.Tag:Myr(Src42A).Tag:HA
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General Information
Symbol
Dmel\cnk5xAIR.UAS.Tag:Myr(Src42A).Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0336639
Feature type
allele
Associated gene
Dmel\cnk
Associated Insertion(s)
Carried in Construct
P{UAS-Myr-cnk.5xAIR.HA}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Wolfstetter et al., 2017)
Progenitor genotype
Carried in construct
P{UAS-Myr-cnk.5xAIR.HA}
Cytology
Description

UAS regulatory sequences drive expression of five tandem repeats of the minimal Alk interaction region (AIR) of cnk (residues 1384-1425). The protein is tagged at the N-terminal end with the Tag:Myr(Src42A) membrane localization signal and at the C-terminal end with three copies of Tag:HA.

(Wolfstetter et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
cnk
Tagged with
Tag:HA
Tag:Myr(Src42A)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of cnk5xAIR.Scer\UAS.T:Myr-Src42A.T:Ivir\HA1 under the control of Scer\GAL4sev.PU does not induce any overt morphological defects in the adult eye.

      (Wolfstetter et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The disrupted morphology of ommatidia in the anterior part of the adult eye of flies expressing AlkScer\UAS.cLa under the control of Scer\GAL4sev.PU is strongly suppressed by co-expression of cnk5xAIR.Scer\UAS.T:Myr-Src42A.T:Ivir\HA1.

      (Wolfstetter et al., 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      cnk5xAIR.Scer\UAS.T:Myr-Src42A.T:Ivir\HA1
      cnk5xAIR.UAS.Tag:Myr(Src42A).Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)