The 'R48B04' enhancer fragment regulates expression of a lexA::UnkAD driver.
Ecol\lexAGMR48B04 positive dopaminergic PAM neurons are in close proximity with Scer\GAL4VT001211 expressing mushroom body medial lobe arborizing neurons 4 and 6 as shown by a positive GFP reconstitution across synaptic partners (GRASP) signal.
Ecol\lexAGMR48B04 drives expression in PAM neurons, including dopaminergic PAM neurons in mushroom body beta' lobe slice 2 that also show expression driven by Scer\GAL4LpR1-0104-G4.
memory defective | adult stage | heat sensitive, with Ecol\lexAdsRNA.UAS.cWa, Scer\GAL4LpR1-0104-G4, shits.lexAop.cLa
Blocking the output (using shits.lexAop.cLa at 33[o]C) of a subset (restricted using Scer\GAL4LpR1-0104-G4 and Ecol\lexAdsRNA.UAS.cWa, to remove expression from Scer\GAL4LpR1-0104-G4 neurons) of Ecol\lexAGMR48B04 neurons shortly before and during training significantly impairs short term memory in starved flies trained with arabinose, compared to controls.