FlyBase Allele Report: Dmel\zld[RNAi.RD.3.UAS]

FB2025_01 , released February 20, 2025

FB2025_01 , released February 20, 2025

Allele: Dmel\zld^{RNAi.RD.3.UAS}

General Information

Symbol

Dmel\zld^{RNAi.RD.3.UAS}

Species

D. melanogaster

Name

FlyBase ID

FBal0337838

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{UAS-zld.RNAi.RD.3}

Key Links

Transgenic product class

(Reichardt et al., 2018)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Reichardt et al., 2018)

Mutagen

in vitro construct

(Reichardt et al., 2018)

Progenitor genotype

Carried in construct

P{UAS-zld.RNAi.RD.3}

Cytology

Description

UAS regulatory sequences (derived from the Walium20 vector) drive expression of a shRNA that targets the zld-RD isoform.

(Reichardt et al., 2018)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Also carries

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

zld^{RNAi.RD.3.UAS}/Scer\GAL4^wor.PA, Scer\GAL80^ase.PN is a suppressor of neoplasia | adult stage phenotype of Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, brat^GD7073

(Reichardt et al., 2018)

zld^{RNAi.RD.3.UAS}/Scer\GAL4^wor.PA, Scer\GAL80^ase.PN is a suppressor of neoplasia | larval stage phenotype of Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, brat^GD7073

(Reichardt et al., 2018)

Phenotype Manifest In

Suppressor of

Statement

Reference

zld^{RNAi.RD.3.UAS}/Scer\GAL4^wor.PA, Scer\GAL80^ase.PN is a suppressor of adult brain phenotype of Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, brat^GD7073

(Reichardt et al., 2018)

zld^{RNAi.RD.3.UAS}/Scer\GAL4^wor.PA, Scer\GAL80^ase.PN is a suppressor of larval brain phenotype of Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, brat^GD7073

(Reichardt et al., 2018)

zld^{RNAi.RD.3.UAS}/Scer\GAL4^wor.PA, Scer\GAL80^ase.PN is a suppressor of type II neuroblast | third instar larval stage phenotype of Scer\GAL4^wor.PA, Scer\GAL80^ase.PN, brat^GD7073

(Reichardt et al., 2018)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

zld^{RNAi.RD.3.UAS}

zld^{shRNA.RD.3.Scer\UAS}

zld^{shRNA.RD.3.UAS}

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections