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General Information
Symbol
Dmel\sqhEE.UAS.ALD.mCherry
Species
D. melanogaster
Name
FlyBase ID
FBal0337946
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drives expression of a constitutively active form of sqh. The protein is tagged at the N-terminal end with the Tag:ALD(insc) apical localization domain and at the C-terminal end with mCherry.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of sqhEE.Scer\UAS.ALD.T:Disc\RFP-mCherry under the control of Scer\GAL4wor.PA (thus forcing constitutively activated Myosin to the apical cortex) in third instar larval neuroblasts leads to abnormalities in cell shape changes from early anaphase to telophase during asymmetric cell division: the furrowing is initiated closer to the apical surface than in wild-type neuroblast (and no subsequent basal shifting of the ingression is observed). Occasionally, the sqhEE.Scer\UAS.ALD.T:Disc\RFP-mCherry expression can cause the neuroblasts to divide symmetrically or with inverted physical asymmetry.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
sqhEE.Scer\UAS.ALD.T:Disc\RFP-mCherry
sqhEE.UAS.ALD.mCherry
Name Synonyms
Secondary FlyBase IDs
    References (1)