FB2025_01 , released February 20, 2025
Allele: Dmel\RhoBTBUAS.cSa
Open Close
General Information
Symbol
Dmel\RhoBTBUAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct of Straub
FlyBase ID
FBal0338007
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Carried in construct
Cytology
Description

UAS regulatory sequences drive expression of a RhoBTB cDNA.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 1 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Flies expressing RhoBTBScer\UAS.cSa under the control of Scer\GAL4elav.PU are bang sensitive and remain paralyzed or with spasms for a prolonged period of time after vortexing, whereas control flies recover immediately or within a few seconds, they also display reduced climbing ability - a phenotype also observed with Scer\GAL4Toll-6-D42, Scer\GAL4RapGAP1-OK6, Scer\GAL4repo or Scer\GAL4DJ757-driven expression of RhoBTBScer\UAS.cSa (but the effect with the latter three is weaker).

Expression controlled by either Scer\GAL4elav.PU or Scer\GAL4Mef2.247 does not significantly impair either learning or short- or long-term memory tested in a courtship conditioning paradigm.

Expression of RhoBTBScer\UAS.cSa driven by Scer\GAL4RapGAP1-OK6, Scer\GAL4Toll-6-D42 or Scer\GAL4elav.PU does not induce any significant alterations in the morphology of neuromuscular junctions in third instar larvae and expression under the combined control of Scer\GAL4477 and Scer\GAL4ppk.PG does not the formation of the dendritic arbor (number and length of dendritic branches) in larval class IV dendritic arborizing neurons

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
RhoBTBScer\UAS.cSa
RhoBTBUAS.cSa
Name Synonyms
Saccharomyces cerevisiae UAS construct of Straub
Secondary FlyBase IDs
    References (1)