FB2025_05 , released December 11, 2025
Allele: Dmel\SmnΔ7S.v.Tag:FLAG
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General Information
Symbol
Dmel\SmnΔ7S.v.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0338035
Feature type
allele
Associated gene
Dmel\Smn
Associated Insertion(s)
Carried in Construct
M{Flag-vSmn.Δ7S}
Key Links
Transgenic product class
inframe_deletion
(Gray et al., 2018)
missense_variant
(Gray et al., 2018)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Gray et al., 2018)
missense_variant
(Gray et al., 2018)
Mutagen
in vitro construct
(Gray et al., 2018)
Progenitor genotype
Smnv.Tag:FLAG
(Gray et al., 2018)
Carried in construct
M{Flag-vSmn.Δ7S}
Cytology
Description

The Smn coding region has been truncated so that it resembles the truncated, unstable 'SMNΔ7' product produced from the orthologous human SMN2 gene.

(Gray et al., 2018)
Allele components
Component
Use(s)
Regulatory region(s)
Smn
Encoded product / tool
Smn
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  childhood spinal muscular atrophy
      CEA
      (Gray et al., 2018)
      CEA with SmnX7
      (Gupta et al., 2021)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      SmnΔ7S.v.Tag:FLAG fails to rescue SmnX7

      (Gupta et al., 2021)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      SmnΔ7S.v.T:Zzzz\FLAG
      SmnΔ7S.v.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (2)