A TI{CRIMIC.TG4.0} DNA cassette has been inserted into Adhr, in a coding intron, and is predicted to gene trap all annotated transcripts of the gene. The insertion is also within Adh, in the 3' UTR of 2 out of 5 its annotated transcripts. The insertion is also within osp, in a coding intron, and is not predicted to gene trap this gene. The TI{CRIMIC.TG4.0} cassette was inserted using the CRISPR/Cas9 technique together with a donor plasmid to drive homology directed repair. The sgRNA sequence used to target the gene was: ATTAAGTTTATGTTTCAGTTCGG. The homology arms of the donor plasmid used were designed such that there is a small gap between the 3' end of the 5' arm and the 5' end of the 3' arm, thus the insertion of the TI{CRIMIC.TG4.0} cassette is predicted to be accompanied by a deletion of 26bp of genomic sequence flanking the insertion site.