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General Information
Symbol
Dmel\SIFa2
Species
D. melanogaster
Name
FlyBase ID
FBal0343274
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
deletion
Comment:

A 318bp deletion that removes both exons of SIFa maps to 2R:24577763-24578080 .

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Deletion covering both exons of SIFa ( 2R:24577763-24578080 ).

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Disease
Interaction
References
DOES NOT ameliorate  sleep disorder
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

SIFa2 homozygotes and SIFa2/SIFa3 transheterozygotes show a significant decrease in sleep time, as compared to heterozygous and wild-type controls.

SIFa2/Df(2R)BSC780 transheterozygotes and SIFa2 homozygotes are mostly circadian rhythmic, although with a lower rhythmic strength, as compared to heterozygous and wild-type controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference

SIFa3/SIFa2 has sleep defective phenotype, enhanceable by Nf1P2/Nf1P1

NOT Enhancer of
Statement
Reference

SIFa[+]/SIFa2 is a non-enhancer of sleep defective phenotype of Nf1P2/Nf1P1

SIFa3/SIFa2 is a non-enhancer of sleep defective phenotype of Nf1P2/Nf1P1

NOT Suppressor of
Statement
Reference

SIFa[+]/SIFa2 is a non-suppressor of sleep defective phenotype of Nf1P2/Nf1P1

SIFa3/SIFa2 is a non-suppressor of sleep defective phenotype of Nf1P2/Nf1P1

Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (2)