FB2025_04 , released October 2, 2025
Allele: Hsap\FUSUAS.cYa
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General Information
Symbol
Hsap\FUSUAS.cYa
Species
H. sapiens
Name
UAS construct a of Yamamoto
FlyBase ID
FBal0343573
Feature type
allele
Associated gene
Hsap\FUS
Associated Insertion(s)
Carried in Construct
P{UAS-hFUS.Y}
Key Links
Transgenic product class
cDNA
(Yamamoto et al., 2018)
wild_type
(Yamamoto et al., 2018)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Yamamoto et al., 2018)
wild_type
(Yamamoto et al., 2018)
Mutagen
in vitro construct
(Yamamoto et al., 2018)
Progenitor genotype
Carried in construct
P{UAS-hFUS.Y}
Cytology
Description

UASt regulatory sequences drive expression of a Hsap\FUS cDNA.

(Yamamoto et al., 2018)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Hsap\FUS
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  amyotrophic lateral sclerosis type 6
      CEC
      (Yamamoto et al., 2018)
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      model of  amyotrophic lateral sclerosis type 6
      is ameliorated by Hsap\MLF1::Hsap\NPM1UAS.cYa
      (Yamamoto et al., 2018)
      Comments on Models/Modifiers Based on Experimental Evidence ( 1 )
       

      FlyBase curator comment: "amyotrophic lateral sclerosis type 6" is associated with human ortholog FUS.

      (Yamamoto et al., 2018)
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Hsap\FUSUAS.cYa
      Name Synonyms
      UAS construct a of Yamamoto
      Secondary FlyBase IDs
        References (1)