FB2021_01, released Feb 18, 2021

Allele: Scer\GAL4R42G02

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General Information
Symbol
Scer\GAL4R42G02
Species
S. cerevisiae
Name
FlyBase ID
FBal0344088
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{R42G02-GAL4}
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
in vitro construct - regulatory fusion
(Zhou et al., 2014)
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
       
      Progenitor genotype
      Carried in construct
      P{R42G02-GAL4}
      Cytology
      Nature of the lesion
      Statement
      Reference

      4089bp GMR42G02 fragment from the dsx region is fused upstream of a Drosophila synthetic core promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

      (Zhou et al., 2014)
      Allele components
      Product class / Tool use(s)
      Encoded product / tool
      GAL4
      Associated Sequence Features
      GMR42G02
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      proboscis | restricted
      (Zhou et al., 2014)
      adult head | restricted
      (Zhou et al., 2014)
      skeletal muscle of thorax | faint | subset
      (Zhou et al., 2014)
      adult stage | male
      surstylus | restricted
      (Zhou et al., 2014)
      epandrial ventral lobe | restricted
      (Zhou et al., 2014)
      ejaculatory bulb | restricted
      (Zhou et al., 2014)
      adult doublesex AbN (male) neuron | subset
      (Zhou et al., 2014)
      adult stage | female
      female terminalia | restricted
      (Zhou et al., 2014)
      adult doublesex AbN (female) neuron | subset
      (Zhou et al., 2014)
      Additional Information
      Statement
      Reference

      Scer\GAL4R42G02 drives expression in a epithelium of the proboscis and head, faintly in a dorsal thoracic muscle and in the macrochaetae of the clasper and lateral plate of the male, the base of the ejaculatory bulb, and a subcuticular epithelium of the female terminalia.

      (Zhou et al., 2014)
       
      Marker for
      Reflects expression of
      dsx
      (Zhou et al., 2014)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Thermogenetic activation (using TrpA1UAS.(B).cKa at 27[o]C) of Scer\GAL4R42G02 cells in adult virgin females significantly reduces copulation within 10 min of introduction to a male, compared to baseline, unlike controls.

      (Zhou et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4R42G02
      Name Synonyms
      Secondary FlyBase IDs
        References (2)