FB2025_05 , released December 11, 2025
Allele: Ecol\lexAVT040556.PU
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General Information
Symbol
Ecol\lexAVT040556.PU
Species
E. coli
Name
FlyBase ID
FBal0344098
Feature type
allele
Associated gene
Ecol\lexA
Associated Insertion(s)
Carried in Construct
P{VT040556-lexA.U}
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(FlyBase Curators, 2025-)
Progenitor genotype
Carried in construct
P{VT040556-lexA.U}
Cytology
Description

The VT040556 fragment drives expression of a lexA::UnkAD driver.

(FlyBase Curators, 2025-)

FlyBase curator comment: this entry represents a transgenic construct where the particular construct used cannot be determined.

(FlyBase Curators, 2025-)
Allele components
Component
Use(s)
Regulatory region(s)
VT040556
Encoded product / tool
lexA::UnkAD
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Optogenetic activation (using Crei\ChR1ReaChR.lexAop.FRT.mCherry.Citrine with 590 nm (yellow) light) of Ecol\lexAVT040556 neurons that express Scer\FLP1fru in adult males results in the induction of pulse song in the absence of a female, this song is similar to the natural pulse song of these flies when singing to a female; pulse song is not induced and flight is not affected by activation while the fly is flying; disruption of leg-ground contact during activation-induced song is sufficient to initiate flight.

      (O'Sullivan et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Optogenetic activation (using Cnoc\ChR1Cs.IVS.20xUAS.Venus with 590 nm (yellow) light) of Scer\GAL4Tdc2.PC neurons suppresses the induction of pulse song observed due to optogenetic activation (using Crei\ChR1ReaChR.lexAop.FRT.mCherry.Citrine with 590 nm (yellow) light) of Ecol\lexAVT040556 neurons that express Scer\FLP1fru in adult males.

      (O'Sullivan et al., 2018)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ecol\lexAVT040556.PU
      Ecol\lexAVT040556
      Name Synonyms
      Secondary FlyBase IDs
        References (3)