FB2025_01 , released February 20, 2025
Allele: Dmel\FoxPUASp.I1
Open Close
General Information
Symbol
Dmel\FoxPUASp.I1
Species
D. melanogaster
Name
FlyBase ID
FBal0346731
Feature type
allele
Associated gene
Dmel\FoxP
Associated Insertion(s)
Carried in Construct
P{UASp-FoxP.I1}
Key Links
Transgenic product class
cDNA
(Castells-Nobau et al., 2019)
wild_type
(Castells-Nobau et al., 2019)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Castells-Nobau et al., 2019)
wild_type
(Castells-Nobau et al., 2019)
Mutagen
in vitro construct
(Castells-Nobau et al., 2019)
Progenitor genotype
Carried in construct
P{UASp-FoxP.I1}
Cytology
Description

UASp regulatory sequences drive expression of FoxP isoform 1 (cDNA sequence).

(Castells-Nobau et al., 2019)
Allele components
Component
Use(s)
Regulatory region(s)
UASp
Encoded product / tool
FoxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Individuals expressing FoxPUASp.I1 under the control of Scer\GAL4Mef2.247 show significantly larger mushroom body α-lobe tips than controls.

      Individuals expressing FoxPUASp.I1 under the control of Scer\GAL4elav.PLu show a significant increase in light-off jump habituation, as they show a slight decrease in jump response in the course of the assay, and only show an increase in social distances (distance to the closest neighbor) at >0.5cm, as compared to controls.

      Third instar larval neuromuscular junction of individuals expressing FoxPUASp.I1 under the control of Scer\GAL4elav.PLu do not show any apparent defects, including number of branches and postsynaptic size, as compared to controls.

      Third instar larval class IV da neurons of individuals expressing FoxPUASp.I1 under the control of Scer\GAL4477 do not exhibit significant changes in dendritic tree morphology, including dendritic field area, dendritic length and number of dendritic endings, as compared to controls.

      (Castells-Nobau et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      FoxPUASp.I1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)