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General Information
Symbol
Dmel\CG9003indel
Species
D. melanogaster
Name
FlyBase ID
FBal0350185
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Mutagen
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
complex substitution
Comment:

Inferred location of a 4bp deletion and 74bp insertion in the second coding exon of CG9003. The double strand break is reported as occurring 15 nucleotides downstream of the ATG for isoform CG9003- RC. The first three nucleotides of the inserted sequence encode a stop codon (TAA). The mapped location of the 4 base deletion is approximate.

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Indel mutation (4bp deletion, 74bp insertion) within the second coding exon of CG9003. The mutation is predicted to result in a truncated protein as the first 3 nucleotides of the 74bp insertion encode a TAA stop codon.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

While mushroom body gamma neurons of CG9003indel homozygotes grow normally, adult mushroom bodies consistently display pruning defects.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
Phenotype Manifest In
Enhanced by
Statement
Reference

CG9003indel has gamma Kenyon cell | adult stage phenotype, enhanceable by slmb3A1/slmb[+]

CG9003indel has axon | adult stage phenotype, enhanceable by slmb3A1/slmb[+]

Additional Comments
Genetic Interactions
Statement
Reference

CG9003indel homozygous adults show mushroom body gamma neuron pruning defects, which become more severe in a slmb3A1 heterozygous background.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (1)